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Western Blot (WB) (Western Blot detection against Immunogen (37.11kD).)

Mouse anti-Human PKD2L1 Monoclonal Antibody | anti-PKD2L1 antibody

PKD2L1 (Polycystic Kidney Disease 2-like 1 Protein, Polycystin-2 Homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1, PKD2L, PKDL, TRPP3)

Gene Names
PKD2L1; PCL; PKDL; PKD2L; TRPP3
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
PKD2L1; Monoclonal Antibody; PKD2L1 (Polycystic Kidney Disease 2-like 1 Protein; Polycystin-2 Homolog; Polycystin-2L1; Polycystin-L; Polycystin-L1; PKD2L; PKDL; TRPP3); Anti -PKD2L1 (Polycystic Kidney Disease 2-like 1 Protein; anti-PKD2L1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
4F9
Specificity
Recognizes human PKD2L1.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
KWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYL
Applicable Applications for anti-PKD2L1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Immunogen
Partial recombinant corresponding to aa173-273 from PKD2L1 (NP_057196) with GST tag. MW of the GST tag alone is 26kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (37.11kD).)

Western Blot (WB) (Western Blot detection against Immunogen (37.11kD).)
Related Product Information for anti-PKD2L1 antibody
PKD2L1 is a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined.
Product Categories/Family for anti-PKD2L1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
91,982 Da
NCBI Official Full Name
polycystic kidney disease 2-like 1 protein isoform 2
NCBI Official Synonym Full Names
polycystic kidney disease 2-like 1
NCBI Official Symbol
PKD2L1
NCBI Official Synonym Symbols
PCL; PKDL; PKD2L; TRPP3
NCBI Protein Information
polycystic kidney disease 2-like 1 protein; polycystin-L; polycystin-L1; polycystin-2L1; polycystin-2 homolog; transient receptor potential cation channel, subfamily P, member 3
UniProt Protein Name
Polycystic kidney disease 2-like 1 protein
UniProt Gene Name
PKD2L1
UniProt Synonym Gene Names
PKD2L; PKDL
UniProt Entry Name
PK2L1_HUMAN

NCBI Description

This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Uniprot Description

Function: May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling. Ref.8

Subcellular location: Membrane; Multi-pass membrane protein

Potential.

Tissue specificity: Expressed in adult heart, skeletal muscle, brain, spleen, testis, retina and liver. According to Ref.1, expressed at high levels in fetal tissues, including kidney and liver, and down-regulated in adult tissues. According to Ref.7, expressed in fetal brain, but not expressed in fetal lung, liver or kidney. Isoform 4 appears to be expressed only in transformed lymphoblasts. Ref.1 Ref.7

Sequence similarities: Belongs to the polycystin family.

Research Articles on PKD2L1

Similar Products

Product Notes

The PKD2L1 pkd2l1 (Catalog #AAA647104) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PKD2L1 (Polycystic Kidney Disease 2-like 1 Protein, Polycystin-2 Homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1, PKD2L, PKDL, TRPP3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PKD2L1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the PKD2L1 pkd2l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: KWYNNQSLGH GSHSFIYYEN MLLGVPRLRQ LKVRNDSCVV HEDFREDILS CYDVYSPDKE EQLPFGPFNG TAWTYHSQDE LGGFSHWGRL TSYSGGGYYL. It is sometimes possible for the material contained within the vial of "PKD2L1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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