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Western Blot (WB) (Western Blot analysis in HL-60 cell line lysates (35ug/lane) using MBS646468. PLVAP (arrow) was detected using MBS646468.)

Rabbit anti-Human PLVAP Polyclonal Antibody | anti-PLVAP antibody

PLVAP, ID (PLVAP, FELS, PV1, Plasmalemma vesicle-associated protein, Fenestrated endothelial-linked structure protein, Plasmalemma vesicle protein 1)

Gene Names
PLVAP; PV1; FELS; PV-1; gp68
Reactivity
Human
Applications
ELISA, Western Blot, Flow Cytometry, Functional Assay
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
PLVAP; Polyclonal Antibody; ID (PLVAP; FELS; PV1; Plasmalemma vesicle-associated protein; Fenestrated endothelial-linked structure protein; Plasmalemma vesicle protein 1); Anti -PLVAP; anti-PLVAP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-PLVAP antibody
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Western Blot, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50
Immunogen
PLVAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221~250 amino acids from the Center region of human PLVAP.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in HL-60 cell line lysates (35ug/lane) using MBS646468. PLVAP (arrow) was detected using MBS646468.)

Western Blot (WB) (Western Blot analysis in HL-60 cell line lysates (35ug/lane) using MBS646468. PLVAP (arrow) was detected using MBS646468.)

Flow Cytometry (FC/FACS)

(Flow Cytometric analysis of HL-60 cells using MBS646468 (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (Flow Cytometric analysis of HL-60 cells using MBS646468 (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-PLVAP antibody
PLVAP involved in the formation of stomatal and fenestral diaphragms of caveolae. This protein may function in microvascular permeability.
Product Categories/Family for anti-PLVAP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,594 Da
NCBI Official Full Name
plasmalemma vesicle-associated protein
NCBI Official Synonym Full Names
plasmalemma vesicle associated protein
NCBI Official Symbol
PLVAP
NCBI Official Synonym Symbols
PV1; FELS; PV-1; gp68
NCBI Protein Information
plasmalemma vesicle-associated protein; plasmalemma vesicle protein 1; fenestrated endothelial-linked structure protein; fenestrated-endothelial linked structure protein; PV-1 protein
UniProt Protein Name
Plasmalemma vesicle-associated protein
UniProt Gene Name
PLVAP
UniProt Synonym Gene Names
FELS; PV1; PV-1
UniProt Entry Name
PLVAP_HUMAN

Uniprot Description

Function: Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability. Ref.6

Subunit structure: Homodimer

By similarity.

Subcellular location: Cell membrane; Single-pass type II membrane protein

By similarity. Membrane › caveola; Single-pass type II membrane protein

By similarity. Cytoplasm › perinuclear region

By similarity. Note: Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endothelia and transendothelial channels. Also colocalized with CAV1 in perinuclear region

By similarity. Ref.7

Tissue specificity: Expressed in lung, kidney, heart, aorta, placenta, muscle, pituitary gland, adrenals, mammary gland, bladder, lymph node, bone marrow, trachea, digestive tract, liver and tumor-associated endothelium. Ref.1 Ref.7

Induction: By phorbol myristate acetate (PMA) or VEGF in endothelial cell culture. Ref.6 Ref.7

Research Articles on PLVAP

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Product Notes

The PLVAP plvap (Catalog #AAA646468) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLVAP, ID (PLVAP, FELS, PV1, Plasmalemma vesicle-associated protein, Fenestrated endothelial-linked structure protein, Plasmalemma vesicle protein 1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PLVAP can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS). Suitable for use in Western Blot, Flow Cytometry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Flow Cytometry: 1:10-50. Researchers should empirically determine the suitability of the PLVAP plvap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLVAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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