Western Blot (WB)
(Sample Data: Representative Western blot with Anti- PLCgamma1 (1:1000) using 3 ug, 10 ug and 30 ug of Jurkat cell lysate.)
Rabbit PLC gamma 1 Polyclonal Antibody | anti-PLCgamma1 antibody
Anti-PLC gamma 1
Reactivity
Western blot human PLCy1PLCy1 from other species may also be detectable.
Applications
Western Blot
Purity
Affinity chromatography
Synonyms
PLC gamma 1; Polyclonal Antibody; Anti-PLC gamma 1; anti-PLCgamma1 antibody
Host
Rabbit
Reactivity
Western blot human PLCy1
PLCy1 from other species may also be detectable.
PLCy1 from other species may also be detectable.
Clonality
Polyclonal
Specificity
Recognizes the PLCgamma1 protein
Purity/Purification
Affinity chromatography
Form/Format
PBS, pH7.4, 0.02% NaN3, 50% glycerol
Applicable Applications for anti-PLCgamma1 antibody
Western Blot (WB)
Application Notes
WB: 18968:19967
Immunogen
Synthetic peptide corresponding to amino acids 769-773 of human PLCgamma1
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Western Blot (WB)
(Sample Data: Representative Western blot with Anti- PLCgamma1 (1:1000) using 3 ug, 10 ug and 30 ug of Jurkat cell lysate.)
Western Blot (WB)
(Sample Data: Representative Western blot with Anti- PLCgamma1 (1:1000) using 3 ug, 10 ug and 30 ug of Jurkat cell lysate.)
Related Product Information for anti-PLCgamma1 antibody
PLCgamma1 or phospholipase C gamma 1 plays an important role in the intracellular transduction of message from receptor-mediated tyrosine kinase activation. PLCgamma1 catalyzes the formation of two second-messenger molecules inositol 1, 4, 5-trisphosphate and diacylglycerol from phosphatidylinositol 4, 5-bisphosphate. PLCgamma1 is a major substrate for heparin-binding growth factor 1 activated tyrosine kinase. PLCgamma1 inhibits growth factor receptor-mediated invasion of breast and prostate tumor cells and is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE (1).
Product Categories/Family for anti-PLCgamma1 antibody
References
1. Ye, K. et al: Phospholipase C-gamma-1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE. Nature 415: 541-544, 2002.
Similar Products
Product Notes
The PLCgamma1 (Catalog #AAA516149) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PLC gamma 1 reacts with Western blot human PLCy1 PLCy1 from other species may also be detectable. and may cross-react with other species as described in the data sheet. AAA Biotech's PLC gamma 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 18968:19967. Researchers should empirically determine the suitability of the PLCgamma1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLC gamma 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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