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Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using MBS7127633(PGA3/PGA4/PGA5 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200))

Rabbit anti-Human PGA3/PGA4/PGA5 Polyclonal Antibody | anti-LOC101929842 antibody

PGA3/PGA4/PGA5 Antibody

Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
PGA3/PGA4/PGA5; Polyclonal Antibody; PGA3/PGA4/PGA5 Antibody; Pepsinogen 3/Pepsinogen 4/Pepsinogen 5; group I (pepsinogen A); anti-LOC101929842 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-LOC101929842 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-1:5000
WB: 1:500-1:2000
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human PGA3/PGA4/PGA5
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using MBS7127633(PGA3/PGA4/PGA5 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using MBS7127633(PGA3/PGA4/PGA5 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7127633(PGA3/PGA4/PGA5 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7127633(PGA3/PGA4/PGA5 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200))

SDS-Page

(Gel: 10%SDS-PAGE, Lysate: 60 ug, Lane: Human liver cancer tissue, Primary antibody: MBS7127633(PGA3/PGA4/PGA5 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes)

SDS-Page (Gel: 10%SDS-PAGE, Lysate: 60 ug, Lane: Human liver cancer tissue, Primary antibody: MBS7127633(PGA3/PGA4/PGA5 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes)
Product Categories/Family for anti-LOC101929842 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
388
NCBI Official Full Name
Pepsin A-3
NCBI Official Symbol
LOC101929842
NCBI Protein Information
pepsin A-3-like
UniProt Protein Name
Pepsin A-3
UniProt Gene Name
PGA3
UniProt Entry Name
PEPA3_HUMAN

NCBI Description

This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015]

Uniprot Description

PGA3: Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. Belongs to the peptidase A1 family.

Protein type: EC 3.4.23.1; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11q12.2

Molecular Function: aspartic-type endopeptidase activity

Biological Process: digestion; proteolysis

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Product Notes

The LOC101929842 pga3 (Catalog #AAA7127633) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PGA3/PGA4/PGA5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PGA3/PGA4/PGA5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-1:5000 WB: 1:500-1:2000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the LOC101929842 pga3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGA3/PGA4/PGA5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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