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Western Blot (WB) (Western blot analysis of Mouse kidney tissue and Mouse liver tissue lysates using NQO2 Polyclonal Antibody at dilution of 1:1000)

Rabbit NQO2 Polyclonal Antibody | anti-NQO2 antibody

NQO2 Polyclonal Antibody

Gene Names
NQO2; QR2; DHQV; DIA6; NMOR2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
NQO2; Polyclonal Antibody; NQO2 Polyclonal Antibody; DHQV; DIA6; EC 1.10.99.2; MGC94180; NAD(P)H dehydrogenase quinone 2; NAD(P)H menadione oxidoreductase 1 dioxin inducible 2; NAD(P)H menadione oxidoreductase 2 dioxin inducible; NMOR2; NQO 2; NRH dehydrogenase [quinone] 2; NRH dehydrogenase; NRH:quinone oxidoreductase 2; OTTHUMP00000015948; OTTHUMP00000015949; OTTHUMP00000015953; Ox 2; Ox2; QR2; Quinone; Quinone reductase 2; Ribosyldihydronicotinamide dehydrogenase [quinone]; Ribosyldihydronicotinamide dehydrogenase; anti-NQO2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1.2mg/mL (varies by lot)
Sequence Length
231
Applicable Applications for anti-NQO2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:1000-1:5000
IHC: 1:50-1:200
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human NQO2
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Mouse kidney tissue and Mouse liver tissue lysates using NQO2 Polyclonal Antibody at dilution of 1:1000)

Western Blot (WB) (Western blot analysis of Mouse kidney tissue and Mouse liver tissue lysates using NQO2 Polyclonal Antibody at dilution of 1:1000)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human tonsil tissue using NQO2 Polyclonal Antibody at dilution of 1:70(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human tonsil tissue using NQO2 Polyclonal Antibody at dilution of 1:70(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NQO2 Polyclonal Antibody at dilution of 1:70(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NQO2 Polyclonal Antibody at dilution of 1:70(×200))
Related Product Information for anti-NQO2 antibody
NQO2 (EC 1.10.99.2) is a flavoprotein that catalyzes the 2-electron reduction of various quinones, redox dyes, and the vitamin K menadione. NQO2 predominantly uses dihydronicotinamide riboside (NRH) as the electron donor. The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Product Categories/Family for anti-NQO2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
26 kDa
NCBI Official Full Name
Ribosyldihydronicotinamide dehydrogenase
NCBI Official Synonym Full Names
N-ribosyldihydronicotinamide:quinone reductase 2
NCBI Official Symbol
NQO2
NCBI Official Synonym Symbols
QR2; DHQV; DIA6; NMOR2
NCBI Protein Information
ribosyldihydronicotinamide dehydrogenase [quinone]
UniProt Protein Name
Ribosyldihydronicotinamide dehydrogenase [quinone]
UniProt Gene Name
NQO2
UniProt Synonym Gene Names
NMOR2; QR2
UniProt Entry Name
NQO2_HUMAN

NCBI Description

This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Uniprot Description

NQO2: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. Belongs to the NAD(P)H dehydrogenase (quinone) family.

Protein type: Oxidoreductase; EC 1.10.99.2

Chromosomal Location of Human Ortholog: 6p25.2

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: electron carrier activity; dihydronicotinamide riboside quinone reductase activity; NADPH dehydrogenase (quinone) activity; metal ion binding

Biological Process: memory

Disease: Breast Cancer

Research Articles on NQO2

Similar Products

Product Notes

The NQO2 nqo2 (Catalog #AAA2561071) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NQO2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NQO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000-1:5000 IHC: 1:50-1:200 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the NQO2 nqo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NQO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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