Western Blot (WB)
(Western Blot analysis of PEPC in 823 cells using PEPC Rabbit pAb at dilution 1/300)
Rabbit anti-Human PEPC Polyclonal Antibody | anti-PEPC antibody
PEPC Rabbit pAb
IHC-P: 1:25-1:100
Western Blot (WB)
(Western Blot analysis of PEPC in 823 cells using PEPC Rabbit pAb at dilution 1/300)
Western Blot (WB)
(Western Blot analysis of PEPC in 823 cells using PEPC Rabbit pAb at dilution 1/300)
Immunohistochemistry (IHC)
(Immunohistochemistry of PEPC in paraffin-embedded Human colon cancer tissue using PEPC Rabbit pAb at dilution 1/25. Predicted cell location: Cytoplasm, Nucleus)
Immunohistochemistry (IHC)
(Immunohistochemistry of PEPC in paraffin-embedded Human colon cancer tissue using PEPC Rabbit pAb at dilution 1/25. Predicted cell location: Cytoplasm, Nucleus)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]
Uniprot Description
PGC: Hydrolyzes a variety of proteins. Belongs to the peptidase A1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Protease; Secreted; EC 3.4.23.3
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: extracellular space
Molecular Function: aspartic-type endopeptidase activity
Biological Process: digestion; proteolysis
Research Articles on PEPC
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Product Notes
The PEPC pgc (Catalog #AAA4759954) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PEPC Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PEPC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:25-1:100. Researchers should empirically determine the suitability of the PEPC pgc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PEPC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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