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Testing Data (Gel: 12%SDS-PAGE Lysate: 50ug 823 cell Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 30 seconds)

Rabbit anti-Human PGC Polyclonal Antibody | anti-PGC antibody

PGC Antibody

Gene Names
PGC; PEPC; PGII
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
PGC; Polyclonal Antibody; PGC Antibody; PEPC; PGII; anti-PGC antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total PGC protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
0.7 mg/ml (varies by lot)
Sequence Length
315
Applicable Applications for anti-PGC antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Immunogen Type
Recombinant Protein
Immunogen Description
Full length fusion protein
Target Name
PGC
Preparation and Storage
Store at -20 degree C

Testing Data

(Gel: 12%SDS-PAGE Lysate: 50ug 823 cell Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 30 seconds)

Testing Data (Gel: 12%SDS-PAGE Lysate: 50ug 823 cell Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 30 seconds)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/25.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/25.)
Related Product Information for anti-PGC antibody
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
Product Categories/Family for anti-PGC antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,208 Da
NCBI Official Full Name
gastricsin isoform 2 preproprotein
NCBI Official Synonym Full Names
progastricsin (pepsinogen C)
NCBI Official Symbol
PGC
NCBI Official Synonym Symbols
PEPC; PGII
NCBI Protein Information
gastricsin
UniProt Protein Name
Gastricsin
UniProt Gene Name
PGC
UniProt Entry Name
PEPC_HUMAN

NCBI Description

This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]

Uniprot Description

Hydrolyzes a variety of proteins.

Research Articles on PGC

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Product Notes

The PGC pgc (Catalog #AAA9406235) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PGC Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PGC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:2000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the PGC pgc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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