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Western Blot (WB) (Western blot analysis of PEP-19 using COS7 whole cell lysates)

Rabbit PEP-19 Polyclonal Antibody | anti-PEP-19 antibody

PEP-19 Antibody

Gene Names
PCP4; PEP-19
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
PEP-19; Polyclonal Antibody; PEP-19 Antibody; Brain specific antigen PCP 4; Brain specific polypeptide PEP 19; Brain specific polypeptide PEP19; Brain-specific antigen PCP-4; Brain-specific polypeptide PEP-19; OTTHUMP00000109191; Pcp4; PCP4_HUMAN; PEP19; Purkinje cell protein 4; anti-PEP-19 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PEP-19 antibody detects endogenous levels of total PEP-19
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
62
Applicable Applications for anti-PEP-19 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human PEP-19
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Dog, Chicken
Similarity
Pig (100%), Bovine (91%), Horse (100%), Sheep (91%), Dog (100%), Chicken (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of PEP-19 using COS7 whole cell lysates)

Western Blot (WB) (Western blot analysis of PEP-19 using COS7 whole cell lysates)
Related Product Information for anti-PEP-19 antibody
Function: Functions as a modulator of calcium-binding by calmodulin. Thereby, regulates calmodulin activity and the different processes it controls (PubMed:19106096, PubMed:23204517, PubMed:27876793). For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways (PubMed:21491429).
Subunit Structure: Binds to both calcium-free and calcium-bound calmodulin. The affinity for the calcium-bound form is 50-fold greater.
Similarity: Mostly intrinsically disordered, with residual structure localized to the IQ domain which mediates the interaction with calmodulin. Belongs to the PCP4 family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 7 kDa
Predicted: 7 kDa
NCBI Official Full Name
calmodulin regulator protein PCP4
NCBI Official Synonym Full Names
Purkinje cell protein 4
NCBI Official Symbol
PCP4
NCBI Official Synonym Symbols
PEP-19
NCBI Protein Information
calmodulin regulator protein PCP4
UniProt Protein Name
Calmodulin regulator protein PCP4
UniProt Gene Name
PCP4
UniProt Synonym Gene Names
PEP191 PublicationManual assertion based on opinion iniRef.3

Uniprot Description

Functions as a modulator of calcium-binding by calmodulin. Thereby, regulates calmodulin activity and the different processes it controls (PubMed:19106096, PubMed:23204517, PubMed:27876793). For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways (PubMed:21491429).

Research Articles on PEP-19

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Product Notes

The PEP-19 pcp4 (Catalog #AAA9609603) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PEP-19 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PEP-19 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the PEP-19 pcp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PEP-19, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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