Immunohistochemistry (IHC)
(Anti-PDIA2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.)
Goat PDIA2 Polyclonal Antibody | anti-PDIA2 antibody
Goat Polyclonal to Human PDIA2
Predicted Reactivity: Orangutan, Gibbon, Monkey, Bovine (at least 90% immunogen sequence identity)
Predicted Reactivity: Orangutan, Gibbon, Monkey, Bovine (at least 90% immunogen sequence identity)
Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 70kD band observed in Human Pancreas lysates (calculated MW of 58.2kD according to NP_006840.2). The observed molecular weight corresponds to the glycosylated form. Recomm...
Immunohistochemistry (IHC)
(Anti-PDIA2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.)
Immunohistochemistry (IHC)
(Anti-PDIA2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.)
Western Blot (WB)
(PDIA2 antibody (0.03 ug/ml) staining of Human Pancreas lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(PDIA2 antibody (0.03 ug/ml) staining of Human Pancreas lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 [PubMed 8561901]).[supplied by OMIM, Mar 2008]
Uniprot Description
PDIA2: Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. Belongs to the protein disulfide isomerase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Isomerase; Endoplasmic reticulum; EC 5.3.4.1
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen
Molecular Function: disulfide oxidoreductase activity; protein binding; protein disulfide isomerase activity; steroid binding; peptidyl-proline 4-dioxygenase activity
Biological Process: protein folding; cell redox homeostasis; peptidyl-proline hydroxylation; protein retention in ER
Research Articles on PDIA2
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Product Notes
The PDIA2 pdia2 (Catalog #AAA243078) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human PDIA2 reacts with Gorilla, Human Predicted Reactivity: Orangutan, Gibbon, Monkey, Bovine (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's PDIA2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:16000), IHC-P (3.75 ug/ml), WB (0.03 - 0.1 ug/ml) Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 70kD band observed in Human Pancreas lysates (calculated MW of 58.2kD according to NP_006840.2). The observed molecular weight corresponds to the glycosylated form. Recomm.. Researchers should empirically determine the suitability of the PDIA2 pdia2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDIA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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