Testing Data
(Sample (30ug whole cell lysate)A: Hep G2 7.5% SDS PAGEPrimary antibody diluted at 1: 1000)
Rabbit anti-Human PCCase beta Polyclonal Antibody | anti-PCCase beta antibody
PCCase beta antibody
Immunohistochemistry: 1:100-1:250
Immunofluorescence: 1:100-1:200
Testing Data
(Sample (30ug whole cell lysate)A: Hep G2 7.5% SDS PAGEPrimary antibody diluted at 1: 1000)
Testing Data
(Sample (30ug whole cell lysate)A: Hep G2 7.5% SDS PAGEPrimary antibody diluted at 1: 1000)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Lung Ad Cancer PC14 xenograft, using PCCB antibody at 1: 100 dilution.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Lung Ad Cancer PC14 xenograft, using PCCB antibody at 1: 100 dilution.)
Immunofluorescence (IF)
(Immunofluorescence analysis of methanol-fixed Hep G2, using PCCB antibody at 1: 500 dilution.)
Immunofluorescence (IF)
(Immunofluorescence analysis of methanol-fixed Hep G2, using PCCB antibody at 1: 500 dilution.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
Uniprot Description
PCCB: Defects in PCCB are the cause of propionic acidemia type II (PA-2). PA-2 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein. Belongs to the AccD/PCCB family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 6.4.1.3; Ligase; Carbohydrate Metabolism - propanoate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Mitochondrial
Chromosomal Location of Human Ortholog: 3q21-q22
Cellular Component: mitochondrion; mitochondrial matrix; cytosol
Molecular Function: propionyl-CoA carboxylase activity; ATP binding
Biological Process: fatty acid beta-oxidation; vitamin metabolic process; short-chain fatty acid catabolic process; cellular lipid metabolic process; water-soluble vitamin metabolic process; biotin metabolic process
Disease: Propionic Acidemia
Research Articles on PCCase beta
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Product Notes
The PCCase beta pccb (Catalog #AAA9404118) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PCCase beta antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PCCase beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blotting: 1:500-1:3000 Immunohistochemistry: 1:100-1:250 Immunofluorescence: 1:100-1:200. Researchers should empirically determine the suitability of the PCCase beta pccb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCCase beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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