Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Parvalbumin antibody. Counter stained with hematoxylin.)
Rabbit anti-Human Parvalbumin Polyclonal Antibody | anti-PVALB antibody
Parvalbumin Polyclonal Antibody
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunoprecipitation
Purity
ProA affinity purified
Synonyms
Parvalbumin; Polyclonal Antibody; Parvalbumin Polyclonal Antibody; PVALB; D22S749; MGC116759; Parvalbumin alpha; PRVA; anti-PVALB antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Parvalbumin polyclonal antibody detects endogenous levels of Parvalbumin protein.
Purity/Purification
ProA affinity purified
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
110
Applicable Applications for anti-PVALB antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes
WB: 1:500-1:1,000
IHC: 1:50-1:200
IHC: 1:50-1:200
Immunogen
recombinant protein
Preparation and Storage
Store at 4 degree C after thawing.
Aliquot store at -20 degree C or -80 degree C.
Avoid repeated freeze/thaw cycles.
Aliquot store at -20 degree C or -80 degree C.
Avoid repeated freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Parvalbumin antibody. Counter stained with hematoxylin.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Parvalbumin antibody. Counter stained with hematoxylin.)
Related Product Information for anti-PVALB antibody
Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
12kDa
NCBI Official Full Name
parvalbumin
UniProt Protein Name
Parvalbumin alpha
Protein Family
UniProt Gene Name
PVALB
UniProt Entry Name
PRVA_HUMAN
Uniprot Description
PVA: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Belongs to the parvalbumin family.
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: protein complex; cell soma; axon; cytoplasm; nucleus
Molecular Function: protein homodimerization activity; protein heterodimerization activity; calcium ion binding
Biological Process: cytosolic calcium ion homeostasis
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Product Notes
The Parvalbumin pvalb (Catalog #AAA3013204) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Parvalbumin Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Parvalbumin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP). WB: 1:500-1:1,000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the Parvalbumin pvalb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Parvalbumin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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