Western Blot (WB)
(Western Blot (WB) analysis of Parvalbumin alpha polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:Mouse skeletal muscle tissue lysateLane3:Rat skeletal muscle tissue lysate)
Rabbit Parvalbumin alpha Polyclonal Antibody | anti-PVALB antibody
Parvalbumin alpha Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
Parvalbumin alpha; Polyclonal Antibody; Parvalbumin alpha Polyclonal Antibody; PVALB; Parvalbumin-alpha; anti-PVALB antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Parvalbumin alpha polyclonal antibody detects endogenous levels of Parvalbumin alpha protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
110
Applicable Applications for anti-PVALB antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human Parvalbumin alpha.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of Parvalbumin alpha polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:Mouse skeletal muscle tissue lysateLane3:Rat skeletal muscle tissue lysate)
Western Blot (WB)
(Western Blot (WB) analysis of Parvalbumin alpha polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:Mouse skeletal muscle tissue lysateLane3:Rat skeletal muscle tissue lysate)
Related Product Information for anti-PVALB antibody
Parvalbumin is a small, stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Typically, this protein is broken into three domains, domains AB, CD and EF, each individually containing a helix-loop-helix motif. The AB domain houses a two amino-acid deletion in the loop region, whereas domains CD and EF contain the N-terminal and C-terminal, respectively. Calcium binding proteins like parvalbumin play a role in many physiological processes, namely cell-cycle regulation, second messenger production, muscle contraction, organization of microtubules and vision. Parvalbumin expressing neurons have also been found to be in connection with various areas of clinical interest such as Alzheimer's disease, nervous system disorders, age-related cognitive defects and some forms of cancer.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
~ 15kDa
NCBI Official Full Name
parvalbumin
UniProt Protein Name
Parvalbumin alpha
Protein Family
UniProt Gene Name
PVALB
UniProt Entry Name
PRVA_HUMAN
Uniprot Description
PVA: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Belongs to the parvalbumin family.
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component: protein complex; cell soma; axon; cytoplasm; nucleus
Molecular Function: protein homodimerization activity; protein heterodimerization activity; calcium ion binding
Biological Process: cytosolic calcium ion homeostasis
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Product Notes
The Parvalbumin alpha pvalb (Catalog #AAA3006668) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Parvalbumin alpha Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Parvalbumin alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the Parvalbumin alpha pvalb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Parvalbumin alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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