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Western Blot (WB) (Western blot analysis of extracts of Mouse skeletal muscle tissue, using PVALB antibody.)

Rabbit PVALB Polyclonal Antibody | anti-PVALB antibody

PVALB Antibody

Gene Names
PVALB; D22S749
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Antigen affinity purification
Synonyms
PVALB; Polyclonal Antibody; PVALB Antibody; D22S749; anti-PVALB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (varies by lot)
Sequence Length
110
Applicable Applications for anti-PVALB antibody
Western Blot (WB)
Immunogen
Fusion protein of human PVALB
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7447 / sc-7449 / sc-7448 / sc-25727
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of Mouse skeletal muscle tissue, using PVALB antibody.)

Western Blot (WB) (Western blot analysis of extracts of Mouse skeletal muscle tissue, using PVALB antibody.)
Related Product Information for anti-PVALB antibody
Parvalbumin is a calcium-binding albumin protein with low molecular weight (typically 9-11 kDa). It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is localised in fast-contracting muscles, where its levels are highest, and in the brain and some endocrine tissues. Parvalbumin is a small, stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Typically, this protein is broken into three domains, domains AB, CD and EF, each individually containing a helix-loop-helix motif.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,059 Da
NCBI Official Full Name
parvalbumin alpha
NCBI Official Synonym Full Names
parvalbumin
NCBI Official Symbol
PVALB
NCBI Official Synonym Symbols
D22S749
NCBI Protein Information
parvalbumin alpha
UniProt Protein Name
Parvalbumin alpha
Protein Family
UniProt Gene Name
PVALB
UniProt Entry Name
PRVA_HUMAN

NCBI Description

The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. [provided by RefSeq, Jul 2008]

Uniprot Description

PVA: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Belongs to the parvalbumin family.

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: protein complex; cell soma; axon; cytoplasm; nucleus

Molecular Function: protein homodimerization activity; protein heterodimerization activity; calcium ion binding

Biological Process: cytosolic calcium ion homeostasis

Research Articles on PVALB

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Product Notes

The PVALB pvalb (Catalog #AAA2527100) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PVALB Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PVALB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PVALB pvalb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PVALB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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