Rabbit anti-Human, Mouse PAEP Polyclonal Antibody | anti-PAEP antibody

PAEP Polyclonal Antibody

Cat. Num. AAA2523756

• Gene Names: PAEP; GD; GdA; GdF; GdS; PEP; PAEG; PP14
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity purification
• Synonyms: PAEP; Polyclonal Antibody; PAEP Polyclonal Antibody; GD; GdA; GdF; GdS; PEP; PAEG; PP14; anti-PAEP antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: PBS with 0.05% sodium azide and 50% glycerol, pH 7.4.

• Applicable Applications for anti-PAEP antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:100-1:300
• Immunogen: Recombinant protein of human PAEP
• Note: Centrifuge before opening to ensure complete recovery of vial contents.
• Preparation and Storage: Store at -20 degreee C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of Mouse adrenal gland and liver tissue using PAEP Polyclonal Antibody at dilution of 1:250)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer using PAEP Polyclonal Antibody at dilution of 1:60)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human brain using PAEP Polyclonal Antibody at dilution of 1:60)

Related Product Information for anti-PAEP antibody

Background: This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancyassociated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system.

Product Categories/Family for anti-PAEP antibody

Epigenetics

NCBI and Uniprot Product Information

• NCBI GI #: 85567725
• NCBI GeneID: 5047
• UniProt Accession #: P09466; Q5T6T1; Q9UG92
• Molecular Weight: 21kDa
• NCBI Official Full Name: PAEP protein
• NCBI Official Synonym Full Names: progestagen-associated endometrial protein
• NCBI Official Symbol: PAEP
• NCBI Official Synonym Symbols: GD; GdA; GdF; GdS; PEP; PAEG; PP14
• NCBI Protein Information: glycodelin; PEG; PP14 protein (placental protein 14); alpha uterine protein; glycodelin-A; glycodelin-F; glycodelin-S; pregnancy-associated endometrial alpha-2 globulin; pregnancy-associated endometrial alpha-2-globulin; progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial a; progesterone-associated endometrial protein
• UniProt Protein Name: Glycodelin
• Protein Family: Glycodelin
• UniProt Gene Name: PAEP
• UniProt Synonym Gene Names: GD; PP14; PAEG; PEG
• UniProt Entry Name: PAEP_HUMAN

NCBI Description

This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

PAEP: This protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Belongs to the calycin superfamily. Lipocalin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: extracellular region

Biological Process: transport; multicellular organismal development