Mouse anti-Human KATNAL2 Polyclonal Antibody | anti-KATNAL2 antibody

KATNAL2 (Katanin p60 ATPase-containing Subunit A-like 2, Katanin p60 Subunit A-like 2, p60 katanin-like 2, DKFZp667C165, DKFZP667C165, MGC33211)

Cat. Num. AAA642663

• Reactivity: Human
• Applications: Western Blot, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: KATNAL2; Polyclonal Antibody; KATNAL2 (Katanin p60 ATPase-containing Subunit A-like 2; Katanin p60 Subunit A-like 2; p60 katanin-like 2; DKFZp667C165; DKFZP667C165; MGC33211); Anti -KATNAL2 (Katanin p60 ATPase-containing Subunit A-like 2; anti-KATNAL2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human KATNAL2.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MEYESYYFVKFQKYPKIVKKSSDTAENNLPQRSRGKTRRMMNDSCQNLPKINQQRPRSKTTAGKTGDTKSLNKEHPNQEVVDNTRLENANFGLHISRIRKDSGEENAHPRRGQIIDFQGLLTDAIKGATSELALNTFDHNPDPSERLLKPLSAFIGMNSEMRELAAVVSRDIYLHNPNIKWNDIIGLDAAKQLVKEAVVYPIRYPQLFTGILSPWKGLLLYGPPGTGKTLLAKAVATECKTTFFNISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQRGTASGGEHEGSLRMKTELLVQMDGLARSEDLVFVLAASNLPWELDCAMLRRLEKRILVDLPSREARQAMIYHWLPPVSKSRALELHTELEYSVLSQETEGYSGSDIKLVCREAAMRPVRKIFDALENHQSESSDLPRIQLDIVTTADFLDVLTHTKPSAKNLAQRYSDWQREFESV

• Applicable Applications for anti-KATNAL2 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Suitable for use in Immunofluorescence and Western Blot.; Dilution: Immunofluorescence: 10ug/ml
• Immunogen: Full length human KATNAL2, aa1-466 (NP_112593).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of KATNAL2 expression in transfected 293T cell line by KATN polyclonal antibody. Lane 1: KATNAL2 transfected lysate (51.26kD). Lane 2: Non-transfected lysate.)

Immunofluorescence (IF)

(Immunofluorescence of purified antibody to KATNAL2 on HeLa cell. [antibody concentration 10ug/ml].)

Related Product Information for anti-KATNAL2 antibody

Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.

Product Categories/Family for anti-KATNAL2 antibody

Antibodies; Abs to Enzymes; ATPase

NCBI and Uniprot Product Information

• NCBI GI #: 226371754
• NCBI GeneID: 83473
• NCBI Accession #: NP_112593.2
• NCBI GenBank Nucleotide #: NM_031303.2
• UniProt Accession #: Q8IYT4
• Molecular Weight: 61,253 Da
• NCBI Official Full Name: katanin p60 ATPase-containing subunit A-like 2
• NCBI Official Synonym Full Names: katanin p60 subunit A-like 2
• NCBI Official Symbol: KATNAL2
• NCBI Protein Information: katanin p60 ATPase-containing subunit A-like 2; p60 katanin-like 2
• UniProt Protein Name: Katanin p60 ATPase-containing subunit A-like 2
• Protein Family: Katanin p60 ATPase-containing
• UniProt Gene Name: KATNAL2
• UniProt Synonym Gene Names: Katanin p60 subunit A-like 2
• UniProt Entry Name: KATL2_HUMAN

Uniprot Description

KATNAL2: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. Belongs to the AAA ATPase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; EC 3.6.4.3

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: microtubule; cytoplasm; nucleus

Molecular Function: microtubule binding; microtubule-severing ATPase activity; ATP binding

Biological Process: metabolic process; microtubule severing; cytoplasmic microtubule organization and biogenesis