Immunohistochemistry (IHC)
(Sample Type: mouse embryoSample Type: Frozen section of mouse embryo at et12.5Primary Dilution: 1:500Secondary Dilution: 1:2000Antigen Retrevial method: Citrate buffer (pH=6) Image Submitted By: Frédéric ClotmanUniversité catholique de Louvain )
Rabbit Onecut1 Polyclonal Antibody | anti-ONECUT1 antibody
Onecut1 antibody - C-terminal region
Immunohistochemistry (IHC)
(Sample Type: mouse embryoSample Type: Frozen section of mouse embryo at et12.5Primary Dilution: 1:500Secondary Dilution: 1:2000Antigen Retrevial method: Citrate buffer (pH=6) Image Submitted By: Frédéric ClotmanUniversité catholique de Louvain )
Immunohistochemistry (IHC)
(Sample Type: mouse embryoSample Type: Frozen section of mouse embryo at et12.5Primary Dilution: 1:500Secondary Dilution: 1:2000Antigen Retrevial method: Citrate buffer (pH=6) Image Submitted By: Frédéric ClotmanUniversité catholique de Louvain )
Immunohistochemistry (IHC)
(Immunohistochemistry with mouse embryo tissue)
Immunohistochemistry (IHC)
(Immunohistochemistry with mouse embryo tissue)
Western Blot (WB)
(Onecut1 antibody - C-terminal region validated by WB using Mouse Liver lysate at 1.0ug/ml.)
Western Blot (WB)
(Onecut1 antibody - C-terminal region validated by WB using Mouse Liver lysate at 1.0ug/ml.)
Target Description: Onecut1 is a transcriptional activator. It binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is mportant for liver genes transcription and stimulates the expression of Onecut3 in the developing endoderm.
NCBI and Uniprot Product Information
Uniprot Description
ONECUT1: Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. Important for liver genes transcription. Belongs to the CUT homeobox family.
Protein type: DNA-binding
Cellular Component: nucleus
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; DNA binding; transcription factor activity
Biological Process: spleen development; transcription from RNA polymerase II promoter; anatomical structure morphogenesis; cell fate commitment; transcription, DNA-dependent; regulation of cell-matrix adhesion; glucose metabolic process; liver development; endocrine pancreas development; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; B cell differentiation; pancreas development; epithelial cell development; cilium biogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway; cell differentiation; positive regulation of cell migration; endoderm development
Research Articles on ONECUT1
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Product Notes
The ONECUT1 onecut1 (Catalog #AAA3200664) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Onecut1 antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's Onecut1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the ONECUT1 onecut1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: CKRKEQEHGK DRGNTPKKPR LVFTDVQRRT LHAIFKENKR PSKELQITIS. It is sometimes possible for the material contained within the vial of "Onecut1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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