Western Blot (WB)
(B4GALNT3 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the B4GALNT3 antibody detected the B4GALNT3 protein (arrow).)
Rabbit anti-Human B4GALNT3 Polyclonal Antibody | anti-B4GALNT3 antibody
B4GALNT3 Antibody (Center)
Western Blot (WB)
(B4GALNT3 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the B4GALNT3 antibody detected the B4GALNT3 protein (arrow).)
Western Blot (WB)
(B4GALNT3 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the B4GALNT3 antibody detected the B4GALNT3 protein (arrow).)
Immunohistochemistry (IHC)
(B4GALNT3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of B4GALNT3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(B4GALNT3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of B4GALNT3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
glucosyl residues to form N,N-prime-diacetyllactosediamine
(LacdiNAc, or LDN), a unique terminal structure of cell surface
N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by
OMIM].
Arking, D.E., et al. PLoS ONE 5 (3), E9879 (2010) :
Miller, E., et al. J. Biol. Chem. 283(4):1985-1991(2008)
Huang, J., et al. Mol. Cancer Res. 5(6):543-552(2007)
Ikehara, Y., et al. Glycobiology 16(9):777-785(2006)
NCBI and Uniprot Product Information
NCBI Description
B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM, Aug 2008]
Uniprot Description
B4GALNT3: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N'- diacetyllactosediamine formation on gastric mucosa. Belongs to the chondroitin N- acetylgalactosaminyltransferase family.
Protein type: Membrane protein, integral; Transferase; EC 2.4.1.244
Chromosomal Location of Human Ortholog: 12p13.33
Cellular Component: integral to membrane
Molecular Function: acetylgalactosaminyltransferase activity; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity
Biological Process: metabolic process
Research Articles on B4GALNT3
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Product Notes
The B4GALNT3 b4galnt3 (Catalog #AAA9201017) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 555-584. The B4GALNT3 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's B4GALNT3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the B4GALNT3 b4galnt3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "B4GALNT3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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