Western Blot (WB)
(Western Blot: Sample: Recombinant NFkB2, Mouse.)
Rabbit anti-Mouse Nuclear Factor Kappa B2 (NFkB2) Polyclonal Antibody | anti-NFkB2 antibody
Polyclonal Antibody to Nuclear Factor Kappa B2 (NFkB2)
MGSSHHHH HHSSGLVPRG SHMASMTGGQ QMGRGSEF-ADGPYLVIVE QPKQRGFRFR YGCEGPSHGG LPGASSEKGR KTYPTVKICN YEGPAKIEVD LVTHSDPPRA HAHSLVGKQC SELGVCAVSV GPKDMTAQFN NLGVLHVTKK NMMEIMIQKL QRQRLRSKPQ GLTEAERREL EQEAKELKKV MDLSIVRLRF SAFLRASDGS FSLPLKPVIS QPIHDSKSPG
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant NFkB2, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant NFkB2, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded esophagus tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded esophagus tissue))
NCBI and Uniprot Product Information
Uniprot Description
NFkB-p100: a transcription factor of the nuclear factor-kappaB ( NFkB) group. Precursor of the p52 subunit of the nuclear factor NF-kappa-B, which binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of genes involved in immune response and acute phase reactions. The precursor protein itself does not bind to DNA. LT-beta receptor agonists and LPS induce NF-kappaB/p100 processing to p52 at the level of the ribosome. There are five NFkB proteins in mammals (RelA/NFkB-p65, RelB, c-Rel, NF-_B1/NFkB-p105, and NF-_B2/NFkB-p100). They form a variety of homodimers and heterodimers, each of which activates its own characteristic set of genes. Two spliced isoforms have been identified. Isoform p49 is a subunit of the NF-kappa-B protein complex, which stimulates the HIV enhancer in synergy with p65.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 19 C3|19 38.8 cM
Cellular Component: Bcl3/NF-kappaB2 complex; cytoplasm; cytosol; nucleus
Molecular Function: chromatin binding; DNA binding; DNA binding transcription factor activity; protein binding
Biological Process: extracellular matrix organization; follicular dendritic cell differentiation; germinal center formation; I-kappaB kinase/NF-kappaB signaling; inflammatory response; innate immune response; lymph node development; negative regulation of transcription from RNA polymerase II promoter; NIK/NF-kappaB signaling; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated; response to cytokine; rhythmic process; signal transduction; spleen development; transcription, DNA-dependent
Research Articles on NFkB2
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Product Notes
The NFkB2 nfkb2 (Catalog #AAA2006744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Nuclear Factor Kappa B2 (NFkB2) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Nuclear Factor Kappa B2 (NFkB2) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the NFkB2 nfkb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and its sequence is listed below. MGSSHHHH HHSSGLVPRG SHMASMTGGQ QMGRGSEF-A DGPYLVIVE QPKQRGFRFR YGCEGPSHGG LPGASSEKGR KTYPTVKICN YEGPAKIEVD LVTHSDPPRA HAHSLVGKQC SELGVCAVSV GPKDMTAQFN NLGVLHVTKK NMMEIMIQKL QRQRLRSKPQ GLTEAERREL EQEAKELKKV MDLSIVRLRF SAFLRASDGS FSLPLKPVIS QPIHDSKSPG. It is sometimes possible for the material contained within the vial of "Nuclear Factor Kappa B2 (NFkB2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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