Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Rat Nuclear Factor Polyclonal Antibody | anti-NFE2L2 antibody
Polyclonal Antibody to Nuclear Factor, Erythroid Derived 2 Like Protein 2 (NFE2L2)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:RatTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:RatTissue))
NCBI and Uniprot Product Information
NCBI Description
a basic leucine zipper transcription factor; involved in activating expression of genes with an antioxidant response element (ARE) [RGD, Feb 2006]
Uniprot Description
NRF2: a transcription factor that regulates basal expression and antioxidant induction of a transcription factor for NAD(P)H:quinone oxidoreductase-1 (NQO1) and other detoxifying genes. Targeted for proteasomal degradation by INrf2. Oxidative stress causes its phosphorylation and release from INrf2.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 3q23
Cellular Component: centrosome; chromatin; cytoplasm; cytosol; Golgi apparatus; nucleoplasm; nucleus; plasma membrane
Molecular Function: DNA binding; DNA binding transcription factor activity; protein binding; protein domain specific binding; sequence-specific DNA binding; transcription factor binding
Biological Process: aflatoxin catabolic process; aging; cell redox homeostasis; cellular response to angiotensin; cellular response to fluid shear stress; cellular response to glucose starvation; cellular response to hydrogen peroxide; cellular response to hypoxia; cellular response to laminar fluid shear stress; cellular response to oxidative stress; cellular response to tumor necrosis factor; endoplasmic reticulum unfolded protein response; inflammatory response; negative regulation of cardiac muscle cell apoptotic process; negative regulation of endothelial cell apoptotic process; negative regulation of hematopoietic stem cell differentiation; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; negative regulation of vascular associated smooth muscle cell migration; PERK-mediated unfolded protein response; positive regulation of angiogenesis; positive regulation of blood coagulation; positive regulation of blood vessel endothelial cell migration; positive regulation of gene expression; positive regulation of glucose import; positive regulation of neuron projection development; positive regulation of reactive oxygen species metabolic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-independent protein catabolic process; protein ubiquitination; regulation of embryonic development; regulation of removal of superoxide radicals; regulation of transcription, DNA-templated; transcription from RNA polymerase II promoter
Research Articles on NFE2L2
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Product Notes
The NFE2L2 nfe2l2 (Catalog #AAA2026039) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Nuclear Factor, Erythroid Derived 2 Like Protein 2 (NFE2L2) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Nuclear Factor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the NFE2L2 nfe2l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nuclear Factor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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