Rabbit anti-Mouse Npr2 Polyclonal Antibody | anti-NPR2 antibody
Npr2, ID (Npr2, Atrial natriuretic peptide receptor 2, Atrial natriuretic peptide receptor type B, Guanylate cyclase B)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(Western Blot analysis of mouse heart tissue lysates (35ug/lane) using MBS6007012. This demonstrates that MBS6007012 detected the Npr2 protein (arrow).)
Western Blot (WB)
(Western Blot analysis in mouse heart lysate (20ug) using MBS6007012 (1:1000). Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10,000. Predicted band size: 117kD. Blocking/Dilution buffer: 5% NFDM/TBST.)
NCBI and Uniprot Product Information
Uniprot Description
Function: Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis. Mediates inactivation of the TORC1 complex in response to amino acid starvation. Post-transcriptional regulator of nitrogen permeases. May be involved in putative NPR1-dependent phosphorylation of nitrogen permeases or in the processing and targeting of nitrogen permeases at the level of the endoplasmic reticulum. Involved in cell kill provoked by cisplatin and doxorubicin. Ref.9 Ref.11
Subunit structure: Component of the SEA complex composed of at least IML1/SEA1, RTC1/SEA2, MTC5/SEA3, NPR2, NPR3, SEA4, SEC13 and SEH1. Forms a heterodimer with NPR3. Ref.11
Subcellular location: Vacuole membrane; Peripheral membrane protein Ref.11.
Induction: By urea and proline.
Miscellaneous: Present with 319 molecules/cell in log phase SD medium.
Sequence similarities: Belongs to the NPR2 family.
Sequence caution: The sequence AAB65025.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence AAT92885.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence CAA55721.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
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Product Notes
The Npr2 npr2 (Catalog #AAA6007012) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Npr2, ID (Npr2, Atrial natriuretic peptide receptor 2, Atrial natriuretic peptide receptor type B, Guanylate cyclase B) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Npr2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the Npr2 npr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Npr2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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