SDS-PAGE
(SDS-PAGE analysis of recombinant human soluble CD31 produced in insect cells. Sample was loaded in 10% SDS-polyacrylamide gel under reducing condition and stained with Coomassie blue.)
CD31/PECAM-1 recombinant protein
Human CD31/PECAM-1, soluble
Gene Names
PECAM1; CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM
Reactivity
Human
Purity
> 98% by SDS-PAGE & Coomassie stain
Synonyms
CD31/PECAM-1; Human CD31/PECAM-1; soluble; PECAM-1; CD31; PECA1; GPIIA'; endoCAM; CD31/EndoCAM; CD31/PECAM-1 recombinant protein
Host
Insect cells
Reactivity
Human
Purity/Purification
> 98% by SDS-PAGE & Coomassie stain
Form/Format
Lyophilized
Sequence
QENSFTINSV DMKSLPDWTV QNGKNLTLQC FADVSTTSHV KPQHQM LFYK DDVLFYNISS MKSTESYFIP EVRIYDSGTY KCTVIVNNKE K TTAEYQVLV EGVPSPRVTL DKKEAIQGGI VRVNCSVPEE KAPIHFT IEK LELNEKMVKL KREKNSRDQN FVILEFPVEE QDRVLSFRCQ AR IISGIHMQ TSESTKSELV TVTESFSTPK FHISPTGMIM EGAQLHIK CT IQVTHLAQEF PEIIIQKDKA IVAHNRHGNK AVYSVMAMVE HSG NYTCKVE SSRISKVSSI VVNITELFSK PELESSFTHL DQGERLNLS C SIPGAPPANF TIQKEDTIVS QTQDFTKIAS KSDSGTYICT AGID KVVKKS NTVQIVVCEM LSQPRISYDA QFEVIKGQTI EVRCESISGT LPISYQLLKT SKVLENSTKN SNDPAVFKDN PTEDVEYQCV ADNCH SHAKM LSEVLRVKVI APVDEVQISI LSSKVVESGE DIVLQCAVNE GSGPITYKFY REKEGKPFYQ MTSNATQAFW TKQKASKEQE GEYYCT AFNR ANHASSVPRS KILTVRVILA PWKKTRHHHH HH
Sequence Length
738
Label
His-Tag
SDS-PAGE
(SDS-PAGE analysis of recombinant human soluble CD31 produced in insect cells. Sample was loaded in 10% SDS-polyacrylamide gel under reducing condition and stained with Coomassie blue.)
SDS-PAGE
(SDS-PAGE analysis of recombinant human soluble CD31 produced in insect cells. Sample was loaded in 10% SDS-polyacrylamide gel under reducing condition and stained with Coomassie blue.)
Related Product Information for CD31/PECAM-1 recombinant protein
PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. It is highly expressed at endothelial cell junctions, and also expressed in platelets and in most leukocyte sub-types. The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. PECAM-1 has been implicated in the pathogenesis of various inflammation related disorders, including thrombosis, multiple sclerosis (MS), and rheumatoid arthritis. The human PECAM-1 gene codes for a 738 amino acid transmembrane glycoprotein containing a 118 amino acid cytoplasmic domain, a 19 amino acid transmembrane domain, and a 574 amino acid extracellular domain. Recombinant human PECAM-1 is a 572 amino acid glycoprotein comprising the extracellular domain of PECAM-1. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions.
Product Categories/Family for CD31/PECAM-1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
81,378 Da
NCBI Official Full Name
platelet endothelial cell adhesion molecule
NCBI Official Synonym Full Names
platelet and endothelial cell adhesion molecule 1
NCBI Official Symbol
PECAM1
NCBI Official Synonym Symbols
CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM
NCBI Protein Information
platelet endothelial cell adhesion molecule
UniProt Protein Name
Platelet endothelial cell adhesion molecule
UniProt Gene Name
PECAM1
UniProt Synonym Gene Names
PECAM-1
UniProt Entry Name
PECA1_HUMAN
Uniprot Description
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
Protein type: Cell adhesion; Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q23.3
Cellular Component: extracellular space; plasma membrane; platelet alpha granule membrane
Molecular Function: protein binding
Biological Process: cell recognition; diapedesis; extracellular matrix organization and biogenesis; leukocyte migration; phagocytosis; platelet degranulation; signal transduction
Similar Products
Product Notes
The CD31/PECAM-1 pecam1 (Catalog #AAA692284) is a Recombinant Protein produced from Insect cells and is intended for research purposes only. The product is available for immediate purchase. The Human CD31/PECAM-1, soluble reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: QENSFTINSV DMKSLPDWTV QNGKNLTLQC FADVSTTSHV KPQHQM LFYK DDVLFYNISS MKSTESYFIP EVRIYDSGTY KCTVIVNNKE K TTAEYQVLV EGVPSPRVTL DKKEAIQGGI VRVNCSVPEE KAPIHFT IEK LELNEKMVKL KREKNSRDQN FVILEFPVEE QDRVLSFRCQ AR IISGIHMQ TSESTKSELV TVTESFSTPK FHISPTGMIM EGAQLHIK CT IQVTHLAQEF PEIIIQKDKA IVAHNRHGNK AVYSVMAMVE HSG NYTCKVE SSRISKVSSI VVNITELFSK PELESSFTHL DQGERLNLS C SIPGAPPANF TIQKEDTIVS QTQDFTKIAS KSDSGTYICT AGID KVVKKS NTVQIVVCEM LSQPRISYDA QFEVIKGQTI EVRCESISGT LPISYQLLKT SKVLENSTKN SNDPAVFKDN PTEDVEYQCV ADNCH SHAKM LSEVLRVKVI APVDEVQISI LSSKVVESGE DIVLQCAVNE GSGPITYKFY REKEGKPFYQ MTSNATQAFW TKQKASKEQE GEYYCT AFNR ANHASSVPRS KILTVRVILA PWKKTRHHHH HH. It is sometimes possible for the material contained within the vial of "CD31/PECAM-1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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