Rabbit ANPR-B Polyclonal Antibody | anti-ANPR-B antibody

ANPR-B Rabbit pAb

Cat. Num. AAA4757564

• Gene Names: NPR2; AMDM; ANPb; ECDM; NPRB; SNSK; ANPRB; GUC2B; NPRBi; GUCY2B
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Affinity purified
• Synonyms: ANPR-B; Polyclonal Antibody; ANPR-B Rabbit pAb; AMDM; ANPB; ANPRB; GCB; GUC2B; GUCY2B; Npr2; NPRB; NPRBi; anti-ANPR-B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: ANPRB Antibody detects endogenous levels of total ANPRB
• Purity/Purification: Affinity purified
• Form/Format: Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Applicable Applications for anti-ANPR-B antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000; FC/FACS: 1:50
• Immunogen: A synthesized peptide derived from human ANPRB
• Conjugation: Unconjugated
• Modification: Unmodified
• Preparation and Storage: Store at +4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of ANPRB expression in Human fetal kidney lysate.)

Related Product Information for anti-ANPR-B antibody

Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.

Product Categories/Family for anti-ANPR-B antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 4580422
• NCBI GeneID: 4882
• NCBI Accession #: NP_003986.2
• NCBI GenBank Nucleotide #: NM_003995.3
• UniProt Accession #: P20594; O60871; Q4VAK7; Q5TCV2; Q8TA93; Q9UQ50; B0ZBF2; B0ZBF3; D3DRP3; D3DRP4
• Molecular Weight: 111,208 Da
• NCBI Official Full Name: atrial natriuretic peptide receptor 2
• NCBI Official Synonym Full Names: natriuretic peptide receptor 2
• NCBI Official Symbol: NPR2
• NCBI Official Synonym Symbols: AMDM; ANPb; ECDM; NPRB; SNSK; ANPRB; GUC2B; NPRBi; GUCY2B
• NCBI Protein Information: atrial natriuretic peptide receptor 2
• UniProt Protein Name: Atrial natriuretic peptide receptor 2
• UniProt Gene Name: NPR2
• UniProt Synonym Gene Names: ANPRB; ANP-B; ANPR-B; NPR-B; GC-B

NCBI Description

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]

Uniprot Description

Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.