Rabbit NMT2 Polyclonal Antibody | anti-NMT2 antibody

NMT2 Polyclonal Antibody

Cat. Num. AAA2538450

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity Purification
• Synonyms: NMT2; Polyclonal Antibody; NMT2 Polyclonal Antibody; anti-NMT2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification

• Applicable Applications for anti-NMT2 antibody: Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-100
• Immunogen: Recombinant protein of human NMT2
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47215 / sc-67173
• Preparation and Storage: Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using NMT2 antibody.)

Related Product Information for anti-NMT2 antibody

N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.

NCBI and Uniprot Product Information

• NCBI GI #: 13528864
• NCBI GeneID: 9397
• Molecular Weight: Calculated MW: 57kDa
• NCBI Official Full Name: NMT2 protein, partial
• NCBI Official Synonym Full Names: N-myristoyltransferase 2
• NCBI Official Symbol: NMT2
• NCBI Protein Information: glycylpeptide N-tetradecanoyltransferase 2
• UniProt Protein Name: Glycylpeptide N-tetradecanoyltransferase 2
• Protein Family: Glycylpeptide N-tetradecanoyltransferase
• UniProt Gene Name: NMT2
• UniProt Synonym Gene Names: NMT 2
• UniProt Entry Name: NMT2_HUMAN

NCBI Description

This gene encodes one of two N-myristoyltransferase proteins. N-terminal myristoylation is a lipid modification that is involved in regulating the function and localization of signaling proteins. The encoded protein catalyzes the addition of a myristoyl group to the N-terminal glycine residue of many signaling proteins, including the human immunodeficiency virus type 1 (HIV-1) proteins, Gag and Nef. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Uniprot Description

NMT2: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Belongs to the NMT family.

Protein type: Transferase; EC 2.3.1.97

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: cytoplasm; cytosol; extrinsic to membrane; Golgi apparatus; plasma membrane

Molecular Function: glycylpeptide N-tetradecanoyltransferase activity

Biological Process: N-terminal peptidyl-glycine N-myristoylation; phototransduction, visible light; regulation of rhodopsin mediated signaling; rhodopsin mediated signaling; viral protein processing; viral reproduction; virus assembly