Rabbit anti-Human, Mouse NMT2 Polyclonal Antibody | anti-NMT2 antibody

NMT2 Rabbit pAb

Cat. Num. AAA4758985

• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: NMT2; Polyclonal Antibody; NMT2 Rabbit pAb; N-myristoyltransferase 2; anti-NMT2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purified
• Form/Format: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: 0.4mg/ml (varies by lot)

• Applicable Applications for anti-NMT2 antibody: Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:200-1:1000; IHC-P: 1:25-1:100
• Immunogen: Fusion protein of human NMT2
• Conjugation: Unconjugated
• Modification: Unmodified
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of NMT2 in A549 and hela cells in order using NMT2 Rabbit pAb at dilution 1/400)

Immunohistochemistry (IHC)

(Immunohistochemistry of NMT2 in paraffin-embedded Human breast cancer tissue using NMT2 Rabbit pAb at dilution 1/20. Predicted cell location: Cytoplasm)

Related Product Information for anti-NMT2 antibody

N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases.

NCBI and Uniprot Product Information

• NCBI GI #: 4758816
• NCBI GeneID: 9397
• NCBI Accession #: NP_004799.1
• NCBI GenBank Nucleotide #: NM_004808.2
• UniProt Accession #: O60551; Q53Y38; Q5VUC8; Q9BRB4; B0YJ49
• Molecular Weight: 56,980 Da
• NCBI Official Full Name: glycylpeptide N-tetradecanoyltransferase 2
• NCBI Official Synonym Full Names: N-myristoyltransferase 2
• NCBI Official Symbol: NMT2
• NCBI Protein Information: glycylpeptide N-tetradecanoyltransferase 2; NMT 2; glycylpeptide N-tetradecanoyltransferase 2 variant 3; myristoyl-CoA:protein N-myristoyltransferase 2; peptide N-myristoyltransferase 2; type II N-myristoyltransferase
• UniProt Protein Name: Glycylpeptide N-tetradecanoyltransferase 2
• Protein Family: Glycylpeptide N-tetradecanoyltransferase
• UniProt Gene Name: NMT2
• UniProt Synonym Gene Names: NMT 2
• UniProt Entry Name: NMT2_HUMAN

NCBI Description

N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. [provided by RefSeq, Jul 2008]

Uniprot Description

NMT2: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Belongs to the NMT family.

Protein type: EC 2.3.1.97; Transferase

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: Golgi apparatus; extrinsic to membrane; cytoplasm; plasma membrane; cytosol

Molecular Function: glycylpeptide N-tetradecanoyltransferase activity

Biological Process: rhodopsin mediated signaling; phototransduction, visible light; regulation of rhodopsin mediated signaling; viral reproduction; viral protein processing; N-terminal peptidyl-glycine N-myristoylation; virus assembly