Western Blot (WB)
(WB Suggested Anti-NHLH1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human heart)
Rabbit anti-Cow, Human NHLH1 Polyclonal Antibody | anti-NHLH1 antibody
NHLH1 antibody - N-terminal region
Gene Names
NHLH1; HEN1; NSCL; NSCL1; bHLHa35
Reactivity
Cow, Human
Applications
Western Blot
Purity
Affinity Purified
Synonyms
NHLH1; Polyclonal Antibody; NHLH1 antibody - N-terminal region; anti-NHLH1 antibody
Host
Rabbit
Reactivity
Cow, Human
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: GGPGGGQARGPEPGEPGRKDLQHLSREERRRRRRATAKYRTAHATRERIR
Sequence Length
133
Applicable Applications for anti-NHLH1 antibody
Western Blot (WB)
Homology
Cow: 92%; Human: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NHLH1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(WB Suggested Anti-NHLH1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human heart)
Western Blot (WB)
(WB Suggested Anti-NHLH1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human heart)
Related Product Information for anti-NHLH1 antibody
This is a rabbit polyclonal antibody against NHLH1. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCLThe helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.
Target Description: The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC, LYL1, E2A, and SCLThe helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments.
Product Categories/Family for anti-NHLH1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14kDa
NCBI Official Full Name
helix-loop-helix protein 1
NCBI Official Synonym Full Names
nescient helix-loop-helix 1
NCBI Official Symbol
NHLH1
NCBI Official Synonym Symbols
HEN1; NSCL; NSCL1; bHLHa35
NCBI Protein Information
helix-loop-helix protein 1
UniProt Protein Name
Helix-loop-helix protein 1
Protein Family
UniProt Gene Name
NHLH1
UniProt Synonym Gene Names
BHLHA35; HEN1; HEN-1; bHLHa35; NSCL-1
UniProt Entry Name
HEN1_HUMAN
NCBI Description
The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002]
Uniprot Description
NHLH1: May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.
Chromosomal Location of Human Ortholog: 1q22
Cellular Component: nucleus
Molecular Function: protein dimerization activity
Biological Process: central nervous system development; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; cell differentiation
Research Articles on NHLH1
Similar Products
Product Notes
The NHLH1 nhlh1 (Catalog #AAA3224674) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NHLH1 antibody - N-terminal region reacts with Cow, Human and may cross-react with other species as described in the data sheet. AAA Biotech's NHLH1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the NHLH1 nhlh1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: GGPGGGQARG PEPGEPGRKD LQHLSREERR RRRRATAKYR TAHATRERIR. It is sometimes possible for the material contained within the vial of "NHLH1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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