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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain using MBS1498854 at dilution 1:100)

Rabbit anti-Human Neuromedin-K receptor Polyclonal Antibody | anti-TACR3 antibody

Rabbit anti-human Neuromedin-K receptor polyclonal Antibody(TACR3)

Gene Names
TACR3; NKR; HH11; NK3R; NK-3R; TAC3RL
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
Neuromedin-K receptor; Polyclonal Antibody; Rabbit anti-human Neuromedin-K receptor polyclonal Antibody(TACR3); NKR; NK-3 receptor; NK-3R; Neurokinin B receptor; Tachykinin receptor 3; TACR3; NK3R; TAC3R; anti-TACR3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
465
Applicable Applications for anti-TACR3 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Neuromedin-K receptor protein(356-465aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-14127 / sc-28952
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain using MBS1498854 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain using MBS1498854 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS1498854 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS1498854 at dilution 1:100)
Related Product Information for anti-TACR3 antibody
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,202 Da
NCBI Official Full Name
neuromedin-K receptor
NCBI Official Synonym Full Names
tachykinin receptor 3
NCBI Official Symbol
TACR3
NCBI Official Synonym Symbols
NKR; HH11; NK3R; NK-3R; TAC3RL
NCBI Protein Information
neuromedin-K receptor
UniProt Protein Name
Neuromedin-K receptor
Protein Family
UniProt Gene Name
TACR3
UniProt Synonym Gene Names
NK3R; TAC3R; NKR; NK-3R
UniProt Entry Name
NK3R_HUMAN

NCBI Description

This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008]

Uniprot Description

TACR3: This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: cytoplasm; integral to plasma membrane; nucleus; plasma membrane

Molecular Function: protein binding; tachykinin receptor activity

Biological Process: aging; hyperosmotic salinity response; positive regulation of blood pressure; positive regulation of heart rate; regulation of dopamine metabolic process; response to cocaine; response to estradiol stimulus; response to morphine; tachykinin signaling pathway

Disease: Hypogonadotropic Hypogonadism 11 With Or Without Anosmia

Research Articles on TACR3

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Product Notes

The TACR3 tacr3 (Catalog #AAA1498854) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Neuromedin-K receptor polyclonal Antibody(TACR3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Neuromedin-K receptor can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC:1:20-1:200. Researchers should empirically determine the suitability of the TACR3 tacr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neuromedin-K receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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