Rabbit anti-Rat, Human Nampt Polyclonal Antibody | anti-Nampt antibody

Nampt Antibody

Cat. Num. AAA7136136

• Gene Names: Nampt; Pbef; Pbef1
• Reactivity: Rat, Human
• Applications: ELISA, Western Blot
• Purity: >95%, Antigen Affinity purified & Affinity purified
• Synonyms: Nampt; Polyclonal Antibody; Nampt Antibody; Nicotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (EC 2.4.2.12) (Pre-B-cell colony-enhancing factor 1 homolog) (PBEF) (Visfatin); Pbef1; anti-Nampt antibody

• Host: Rabbit
• Reactivity: Rat, Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Antigen Affinity purified & Affinity purified
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH7.4

• Applicable Applications for anti-Nampt antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:1000-1:5000
• Conjugation: Non-conjugated
• Immunogen: Recombinant Rat Nampt protein (231-491AA)
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot Positive WB detected in: Rat Heart tissue, Rat Liver tissue, Rat Spleen tissue, Rat Kidney tissue, Rat Brain tissue, Hela whole cell lysate All lanes: Nampt antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 56 kDa Observed band size: 56 kDa)

Related Product Information for anti-Nampt antibody

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.

Product Categories/Family for anti-Nampt antibody

Epigenetics and Nuclear Signaling

NCBI and Uniprot Product Information

• NCBI GI #: 29293813
• NCBI GeneID: 297508
• NCBI Accession #: NP_808789.1
• NCBI GenBank Nucleotide #: NM_177928.3
• UniProt Accession #: Q80Z29; Q2VT47
• Molecular Weight: 55,438 Da
• NCBI Official Full Name: nicotinamide phosphoribosyltransferase
• NCBI Official Synonym Full Names: nicotinamide phosphoribosyltransferase
• NCBI Official Symbol: Nampt
• NCBI Official Synonym Symbols: Pbef; Pbef1
• NCBI Protein Information: nicotinamide phosphoribosyltransferase
• UniProt Protein Name: Nicotinamide phosphoribosyltransferase
• Protein Family: Nicotinamide phosphoribosyltransferase
• UniProt Gene Name: Nampt
• UniProt Synonym Gene Names: Pbef1; NAmPRTase; Nampt; PBEF

NCBI Description

has similarity to cytokines but is not secreted; localized to the nucleus and cytoplasm, changes in subcellular localization may be associated with the cell cycle [RGD, Feb 2006]

Uniprot Description

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.