Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse N-Acetyl Beta-D-Glucosaminidase (NAGase) Polyclonal Antibody | anti-NAGase antibody
Polyclonal Antibody to N-Acetyl Beta-D-Glucosaminidase (NAGase)
MGHHHHHHSGS- RRLQKWEL NTYLYAPKDD YKHRMFWREM YSVEEAEQLM TLISAAREYE IEFIYAISPG LDITFSNPKE VSTLKRKLDQ VSQFGCRSFA LLFDDIDHNM CAADKEVFSS FAHAQVSITN EIYQYLGEPE TFLFCPTEYC GT
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Kidney Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Kidney Tissue))
NCBI and Uniprot Product Information
Uniprot Description
OGA: Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl- beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Acetyltransferase; EC 3.2.1.169; EC 3.2.1.52; Hydrolase
Chromosomal Location of Human Ortholog: 19 C3|19 38.75 cM
Cellular Component: cytoplasm; cytosol; membrane; mitochondrion; nucleus
Molecular Function: [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity; beta-N-acetylglucosaminidase activity; beta-N-acetylhexosaminidase activity; histone acetyltransferase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; protein binding
Biological Process: dATP metabolic process; glycoprotein metabolic process; metabolic process; N-acetylglucosamine metabolic process; necrotic cell death; negative regulation of cardiac muscle adaptation; negative regulation of protein glycosylation; positive regulation of calcium ion transport; positive regulation of calcium ion transport into cytosol; positive regulation of cell killing; positive regulation of DNA metabolic process; positive regulation of glucose import; positive regulation of growth hormone secretion; positive regulation of insulin secretion; positive regulation of mitochondrial depolarization; positive regulation of protein complex disassembly; positive regulation of proteolysis; protein deglycosylation; protein targeting to membrane
Research Articles on NAGase
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Product Notes
The NAGase mgea5 (Catalog #AAA2007249) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to N-Acetyl Beta-D-Glucosaminidase (NAGase) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's N-Acetyl Beta-D-Glucosaminidase (NAGase) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the NAGase mgea5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG S- RRLQKWEL NTYLYAPKDD YKHRMFWREM YSVEEAEQLM TLISAAREYE IEFIYAISPG LDITFSNPKE VSTLKRKLDQ VSQFGCRSFA LLFDDIDHNM CAADKEVFSS FAHAQVSITN EIYQYLGEPE TFLFCPTEYC GT. It is sometimes possible for the material contained within the vial of "N-Acetyl Beta-D-Glucosaminidase (NAGase), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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