Western Blot (WB)
(Western blot analysis of anti-PKMYT1 Pabin A375(left) and Y79 (right)cell line lysate. PKMYT1(arrow) was detected using the purified Pab.)
Rabbit anti-Human MYT1 (PKMYT1) Polyclonal Antibody | anti-PKMYT1 antibody
MYT1 (PKMYT1) Antibody (C-term)
Western Blot (WB)
(Western blot analysis of anti-PKMYT1 Pabin A375(left) and Y79 (right)cell line lysate. PKMYT1(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-PKMYT1 Pabin A375(left) and Y79 (right)cell line lysate. PKMYT1(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of PKMYT1 (arrow) using rabbit polyclonal PKMYT1 C-term. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PKMYT1 gene.)
Western Blot (WB)
(Western blot analysis of PKMYT1 (arrow) using rabbit polyclonal PKMYT1 C-term. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PKMYT1 gene.)
Nakajima, H., et al., J. Biol. Chem. 278(28):25277-25280 (2003).
Passer, B.J., et al., Proc. Natl. Acad. Sci. U.S.A. 100(5):2284-2289 (2003).
Okumura, E., et al., Nat. Cell Biol. 4(2):111-116 (2002).
Booher, R.N., et al., J. Biol. Chem. 272(35):22300-22306 (1997).
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Uniprot Description
Myt1: a dual specificity protein kinase of the WEE family. Preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Alternative splice-variant isoforms have been reported.
Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, dual-specificity (non-receptor); Protein kinase, Other; Other group; WEE family
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: nucleoplasm; Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytosol
Molecular Function: protein serine/threonine kinase activity; protein binding; metal ion binding; kinase activity; ATP binding; protein kinase activity
Biological Process: mitosis; regulation of cell cycle; regulation of mitosis; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; protein amino acid phosphorylation; G1/S transition of mitotic cell cycle
Research Articles on PKMYT1
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Product Notes
The PKMYT1 pkmyt1 (Catalog #AAA9211208) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 452-482. The MYT1 (PKMYT1) Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYT1 (PKMYT1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PKMYT1 pkmyt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYT1 (PKMYT1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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