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Western Blot (WB) (Western Blot: Sample: Mouse Cerebellum lysate; Primary Ab: 1ug/ml Rabbit Anti-Mouse MOG Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )

Rabbit anti-Mouse Myelin Oligodendrocyte Glycoprotein (MOG) Polyclonal Antibody | anti-MOG antibody

Polyclonal Antibody to Myelin Oligodendrocyte Glycoprotein (MOG)

Gene Names
Mog; B230317G11Rik
Reactivity
Mouse
Applications
Immunocytochemistry, Immunohistochemistry, ELISA, Western Blot
Purity
Affinity Chromatography
Synonyms
Myelin Oligodendrocyte Glycoprotein (MOG); Polyclonal Antibody; Polyclonal Antibody to Myelin Oligodendrocyte Glycoprotein (MOG); anti-MOG antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against MOG. It has been selected for its ability to recognize MOG in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
0.61mg/ml (varies by lot)
Sequence
Antigen: The target protein is fused with a His-tag and its sequence is listed below.
MGHHHHHHSGSEF-GQ FRVIGPGYPI RALVGDEAEL PCRISPGKNA TGMEVGWYRS PFSRVVHLYR NGKDQDAEQA PEYRGRTELL KETISEGKVT LRIQNVRFSD EGGYTCFFRD HSYQEEAAME LKVEDPFYWV NPG
Sequence Length
247
Applicable Applications for anti-MOG antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunogen
Recombinant MOG (Gly29~Gly153) expressed in E.coli.
Cross Reactivity
Mouse, Rat
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2042199
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Mouse Cerebellum lysate; Primary Ab: 1ug/ml Rabbit Anti-Mouse MOG Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )

Western Blot (WB) (Western Blot: Sample: Mouse Cerebellum lysate; Primary Ab: 1ug/ml Rabbit Anti-Mouse MOG Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )

Western Blot (WB)

(Western Blot: Sample: Recombinant MOG, Mouse.)

Western Blot (WB) (Western Blot: Sample: Recombinant MOG, Mouse.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Mouse Cerebrum Tissue))

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Mouse Cerebrum Tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,271 Da
NCBI Official Full Name
myelin-oligodendrocyte glycoprotein
NCBI Official Synonym Full Names
myelin oligodendrocyte glycoprotein
NCBI Official Symbol
Mog
NCBI Official Synonym Symbols
B230317G11Rik
NCBI Protein Information
myelin-oligodendrocyte glycoprotein
UniProt Protein Name
Myelin-oligodendrocyte glycoprotein
UniProt Gene Name
Mog

Uniprot Description

MOG: Mediates homophilic cell-cell adhesion. Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell- cell communication. Defects in MOG are the cause of narcolepsy type 7 (NRCLP7). Neurological disabling sleep disorder, characterized by excessive daytime sleepiness, sleep fragmentation, symptoms of abnormal rapid-eye-movement (REM) sleep, cataplexy, hypnagogic hallucinations, and sleep paralysis. Cataplexy is a sudden loss of muscle tone triggered by emotions, which is the most valuable clinical feature used to diagnose narcolepsy. Human narcolepsy is primarily a sporadically occurring disorder but familial clustering has been observed. Belongs to the immunoglobulin superfamily. BTN/MOG family. 10 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17 B1|17 19.16 cM

Cellular Component: cell surface; integral component of membrane; membrane; membrane raft; myelin sheath

Biological Process: cell adhesion

Research Articles on MOG

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Product Notes

The MOG mog (Catalog #AAA2005076) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Myelin Oligodendrocyte Glycoprotein (MOG) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Myelin Oligodendrocyte Glycoprotein (MOG) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the MOG mog for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with a His-tag and its sequence is listed below. MGHHHHHHSG SEF-GQ FRVIGPGYPI RALVGDEAEL PCRISPGKNA TGMEVGWYRS PFSRVVHLYR NGKDQDAEQA PEYRGRTELL KETISEGKVT LRIQNVRFSD EGGYTCFFRD HSYQEEAAME LKVEDPFYWV NPG. It is sometimes possible for the material contained within the vial of "Myelin Oligodendrocyte Glycoprotein (MOG), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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