Rabbit anti-Human MYBBP1A Polyclonal Antibody | anti-MYBBP1A antibody

MYBBP1A Antibody

Cat. Num. AAA9401924

• Gene Names: MYBBP1A; P160; PAP2
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: MYBBP1A; Polyclonal Antibody; MYBBP1A Antibody; P160; PAP2; anti-MYBBP1A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total MYBBP1A protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
• Concentration: 2.6 mg/ml (varies by lot)
• Sequence Length: 1332

• Applicable Applications for anti-MYBBP1A antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Western blotting: 1:200-1:1000; Immunohistochemistry: 1:50-1:200
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human MYB binding protein (P160) 1a
• Target Name: MYBBP1A
• Preparation and Storage: Store at -20 degree C

Testing Data

(Gel: 6%SDS-PAGE Lysates (from left to right): HT-29, A549, 293T and Hela cell Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 20 seconds)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)

Related Product Information for anti-MYBBP1A antibody

This gene encodes a nucleolar transcriptional regulator that was first identified by its ability to bind specifically to the Myb proto-oncogene protein. The encoded protein is thought to play a role in many cellular processes including response to nucleolar stress, tumor suppression and synthesis of ribosomal DNA. Alternate splicing results in multiple transcript variants.

Product Categories/Family for anti-MYBBP1A antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 157694494
• NCBI GeneID: 10514
• NCBI Accession #: NP_001099008.1
• NCBI GenBank Nucleotide #: NM_001105538.1
• UniProt Accession #: Q9BQG0; Q86VM3; Q9BW49; Q9P0V5; Q9UF99
• Molecular Weight: 149,367 Da
• NCBI Official Full Name: myb-binding protein 1A isoform 1
• NCBI Official Synonym Full Names: MYB binding protein (P160) 1a
• NCBI Official Symbol: MYBBP1A
• NCBI Official Synonym Symbols: P160; PAP2
• NCBI Protein Information: myb-binding protein 1A
• UniProt Protein Name: Myb-binding protein 1A
• Protein Family: Myb-binding protein
• UniProt Gene Name: MYBBP1A
• UniProt Synonym Gene Names: P160
• UniProt Entry Name: MBB1A_HUMAN

NCBI Description

This gene encodes a nucleolar transcriptional regulator that was first identified by its ability to bind specifically to the Myb proto-oncogene protein. The encoded protein is thought to play a role in many cellular processes including response to nucleolar stress, tumor suppression and synthesis of ribosomal DNA. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.