MRGPRX1 3 4; Polyclonal Antibody; MRGPRX1 3 4 Antibody FITC Conjugated; MRGPRC; G protein coupled receptor MRGX1; G protein coupled receptor SNSR3; GPCR; Mas related G protein coupled receptor member X1; MAS related gene MRGX1; MAS related GPR member X1; MRGPRX1; MRGX1; Sensory neuron specic G protein coupled receptor 3 4; Seven transmembrane helix receptor; SNSR3; SNSR; anti-MRGPRX1 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A
Form/Format
10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration
1mgml (varies by lot)
Applicable Applications for anti-MRGPRX1 antibody
Immunofluorescence (IF)
Application Notes
IF: 1:50-200
Conjugation
FITC
Excitation Emission
494nm 518nm
Immunogen
KLH conjugated synthetic peptide aa 1-35 322 derived from human MRGX1
Preparation and Storage
Store at 4 degree C for 12 months.
Related Product Information for anti-MRGPRX1 antibody
There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G Alpha q- and G Alpha i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G Alpha q-regulated pathways. G Alpha q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha)q proteins are involved in the calcium-signaling pathway.
Product Categories/Family for anti-MRGPRX1 antibody
The MRGPRX1 (Catalog #AAA9461729) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRGPRX1 3 4 Antibody FITC Conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MRGPRX1 3 4 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). IF: 1:50-200. Researchers should empirically determine the suitability of the MRGPRX1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"MRGPRX1 3 4, Polyclonal Antibody" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
any time and without notice. It is the responsibility of the customer to inform AAA Biotech
of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
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