Immunohistochemistry (IHC)
(Anti-MPRIP / RIP3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)
Rabbit MPRIP / RIP3 Polyclonal Antibody | anti-MPRIP antibody
Rabbit Polyclonal (IgG) to Human MPRIP / RIP3
Gene Names
MPRIP; MRIP; RIP3; M-RIP; RHOIP3; p116Rip
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Immunoaffinity Purified
Synonyms
MPRIP / RIP3; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human MPRIP / RIP3; Anti-MPRIP / RIP3 Antibody (aa723-772) IHC-plus; MPRIP; KIAA0864; M-RIP; p116Rip; Rho interacting protein 3; RHOIP3; RIP3; MRIP; Rho-interacting protein 3; Human MPRIP; anti-MPRIP antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MPRIP Antibody detects endogenous levels of total MPRIP protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
1038
Applicable Applications for anti-MPRIP antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes
ELISA (1:40000), IHC-P (5 ug/ml)
Target Species
Human
Immunogen Description
Synthetic peptide from human MPRIP (aa723-772).
Immunogen
MPRIP / RIP3 antibody was raised against synthetic peptide from human MPRIP (aa723-772).
Antigen Modification
aa723-772
Preparation and Storage
Store at -20 degree C for up to one year.
Immunohistochemistry (IHC)
(Anti-MPRIP / RIP3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-MPRIP / RIP3 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
114,049 Da
NCBI Official Full Name
myosin phosphatase Rho-interacting protein isoform 1
NCBI Official Synonym Full Names
myosin phosphatase Rho interacting protein
NCBI Official Symbol
MPRIP
NCBI Official Synonym Symbols
MRIP; RIP3; M-RIP; RHOIP3; p116Rip
NCBI Protein Information
myosin phosphatase Rho-interacting protein; Rho interacting protein 3
UniProt Protein Name
Myosin phosphatase Rho-interacting protein
Protein Family
UniProt Gene Name
MPRIP
UniProt Synonym Gene Names
; M-RIP; RIP3
UniProt Entry Name
MPRIP_HUMAN
Uniprot Description
RIP3: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F- actin-binding region leads to disassembly of stress fibers in neuronal cells. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs; GAPs, Rac/Rho
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: focal adhesion; cytoplasm; actin cytoskeleton
Molecular Function: protein binding; actin binding
Research Articles on MPRIP
Similar Products
Product Notes
The MPRIP mprip (Catalog #AAA244019) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human MPRIP / RIP3 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MPRIP / RIP3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA (1:40000), IHC-P (5 ug/ml). Researchers should empirically determine the suitability of the MPRIP mprip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MPRIP / RIP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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