Rabbit anti-Human MOV10 Polyclonal Antibody | anti-MOV10 antibody

MOV10 Antibody

Cat. Num. AAA7002780

• Gene Names: MOV10; gb110; fSAP113
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >95%,Protein G purified
• Synonyms: MOV10; Polyclonal Antibody; MOV10 Antibody; Putative helicase MOV-10; Moloney leukemia virus 10 protein; KIAA1631; anti-MOV10 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 1003

• Applicable Applications for anti-MOV10 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: Recombinant human Putative helicase MOV-10 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western blotAll lanes: MOV10 antibody at 0.4ug/mlLane 1: Hela whole cell lysateLane 2: HepG-2 whole cell lysateLane 3: 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 114,102,7 kDaObserved band size: 114 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7002780 at dilution of 1:100)

Related Product Information for anti-MOV10 antibody

Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.

NCBI and Uniprot Product Information

• NCBI GI #: 194272168
• NCBI GeneID: 4343
• NCBI Accession #: NP_001123551.1
• NCBI GenBank Nucleotide #: NM_001130079.2
• UniProt Accession #: Q9HCE1; Q5JR03; Q8TEF0; Q9BSY3; Q9BUJ9
• Molecular Weight: 6,546 Da
• NCBI Official Full Name: putative helicase MOV-10 isoform 1
• NCBI Official Synonym Full Names: Mov10 RISC complex RNA helicase
• NCBI Official Symbol: MOV10
• NCBI Official Synonym Symbols: gb110; fSAP113
• NCBI Protein Information: putative helicase MOV-10
• UniProt Protein Name: Putative helicase MOV-10
• Protein Family: Putative helicase
• UniProt Gene Name: MOV10
• UniProt Synonym Gene Names: KIAA1631
• UniProt Entry Name: MOV10_HUMAN

Uniprot Description

MOV10: Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA- mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription. Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.4.13; RNA-binding; RNA processing; Helicase; Spliceosome

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: cytosol; extracellular space

Molecular Function: ATP binding; helicase activity; protein binding

Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; miRNA-mediated gene silencing, mRNA cleavage; nerve growth factor receptor signaling pathway; Notch signaling pathway; phosphoinositide-mediated signaling; regulation of transcription, DNA-dependent; transcription, DNA-dependent