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Western Blot (WB) (MOV10 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the MOV10 antibody detected the MOV10 protein (arrow).)

Rabbit anti-Human MOV10 Polyclonal Antibody | anti-MOV10 antibody

MOV10, NT (MOV10, KIAA1631, Putative helicase MOV-10, Moloney leukemia virus 10 protein) (APC)

Gene Names
MOV10; gb110; fSAP113
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
MOV10; Polyclonal Antibody; NT (MOV10; KIAA1631; Putative helicase MOV-10; Moloney leukemia virus 10 protein) (APC); Moloney leukemia virus 10 protein; anti-MOV10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-MOV10 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
MOV10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-288 amino acids from the N-terminal region of human MOV10.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(MOV10 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the MOV10 antibody detected the MOV10 protein (arrow).)

Western Blot (WB) (MOV10 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the MOV10 antibody detected the MOV10 protein (arrow).)

Immunohistochemistry (IHC)

(MOV10 Antibody (N-term) (AP14933a)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MOV10 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (MOV10 Antibody (N-term) (AP14933a)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MOV10 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-MOV10 antibody
Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.
Product Categories/Family for anti-MOV10 antibody
References
El Messaoudi-Aubert, S., et al. Nat. Struct. Mol. Biol. 17(7):862-868(2010). Furtak, V., et al. PLoS ONE 5 (2), E9081 (2010): Nakano, M., et al. Biochem. Biophys. Res. Commun. 388(2):328-332(2009). Haussecker, D., et al. Nat. Struct. Mol. Biol. 15(7):714-721(2008). Matsuoka, S., et al. Science 316(5828):1160-1166(2007).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
6,546 Da
NCBI Official Full Name
putative helicase MOV-10 isoform 1
NCBI Official Synonym Full Names
Mov10 RISC complex RNA helicase
NCBI Official Symbol
MOV10
NCBI Official Synonym Symbols
gb110; fSAP113
NCBI Protein Information
putative helicase MOV-10
UniProt Protein Name
Putative helicase MOV-10
Protein Family
UniProt Gene Name
MOV10
UniProt Synonym Gene Names
KIAA1631
UniProt Entry Name
MOV10_HUMAN

Uniprot Description

MOV10: Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA- mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription. Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA processing; Helicase; EC 3.6.4.13; Spliceosome

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: extracellular space; cytosol

Molecular Function: protein binding; helicase activity; ATP binding

Biological Process: epidermal growth factor receptor signaling pathway; Notch signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; transcription, DNA-dependent; regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; miRNA-mediated gene silencing, mRNA cleavage; innate immune response

Research Articles on MOV10

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Product Notes

The MOV10 mov10 (Catalog #AAA6321824) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MOV10, NT (MOV10, KIAA1631, Putative helicase MOV-10, Moloney leukemia virus 10 protein) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MOV10 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MOV10 mov10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MOV10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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