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Rabbit anti-Human MFSD2A Polyclonal Antibody | anti-MFSD2A antibody

MFSD2A Conjugated Antibody

Gene Names
MFF; EMPF2; GL004; C2orf33
Reactivity
Human
Applications
Most Applications
Synonyms
MFSD2A; Polyclonal Antibody; MFSD2A Conjugated Antibody; MFSD2; anti-MFSD2A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total MFSD2A protein.
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-MFSD2A antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human major facilitator superfamily domain containing 2A
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
Related Product Information for anti-MFSD2A antibody
MFSD2 (major facilitator superfamily domain containing 2), also known as MFSD2A, is a 543 amino acid multi-pass membrane protein of the endoplasmic reticulum that is involved in beta-adrenergic signaling during thermogenesis. Existing as three alternatively spliced isoforms, MFSD2 plays a role in G1 regulation and is encoded by a gene that maps to human chromosome 1p34.2. Human chromosome 1 spans 260 million base pairs, contains over 3, 000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinsons disease, Gaucher disease, schizophrenia and Usher syndrome.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38kDa
NCBI Official Full Name
mitochondrial fission factor isoform a
NCBI Official Synonym Full Names
mitochondrial fission factor
NCBI Official Symbol
MFF
NCBI Official Synonym Symbols
EMPF2; GL004; C2orf33
NCBI Protein Information
mitochondrial fission factor
UniProt Protein Name
Sodium-dependent lysophosphatidylcholine symporter 1
UniProt Gene Name
MFSD2A
UniProt Synonym Gene Names
MFSD2; NLS1; NLS1; Sodium-dependent LPC symporter 1

NCBI Description

This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Uniprot Description

MFSD2: Plays a role in thermogenesis via beta-adrenergic signaling pathway. May be the main plasma membrane tunicamycin transporter. Belongs to the major facilitator superfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: endoplasmic reticulum membrane; integral component of plasma membrane; plasma membrane

Molecular Function: fatty acid transmembrane transporter activity; lysophospholipid transporter activity; phospholipid transporter activity; symporter activity

Biological Process: fatty acid transport; hippocampus development; lysophospholipid transport; phosphatidylcholine biosynthetic process; transcytosis; transmembrane transport

Disease: Microcephaly 15, Primary, Autosomal Recessive

Research Articles on MFSD2A

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Product Notes

The MFSD2A mfsd2a (Catalog #AAA9448162) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MFSD2A Conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MFSD2A can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the MFSD2A mfsd2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MFSD2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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