Western Blot (WB)
(Western blot analysis of MFSD2A in rat lung tissue lysate with MFSD2A antibody at (A) 1 and (B) 2 ug/mL.)
Rabbit MFSD2A Polyclonal Antibody | anti-MFSD2A antibody
MFSD2A Antibody
Gene Names
mfsd2aa; NLS1-A; mfsd2a; zgc:101615
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
MFSD2A; Polyclonal Antibody; MFSD2A Antibody; Major facilitator superfamily domain-containing protein 2A; anti-MFSD2A antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
532
Applicable Applications for anti-MFSD2A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against an 18 amino acid peptide near the carboxy terminus of human MFSD2A.
Target Name
MFSD2A
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of MFSD2A in rat lung tissue lysate with MFSD2A antibody at (A) 1 and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of MFSD2A in rat lung tissue lysate with MFSD2A antibody at (A) 1 and (B) 2 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of MFSD2A in rat lung tissue with MFSD2A antibody at 5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of MFSD2A in rat lung tissue with MFSD2A antibody at 5 ug/mL.)
Related Product Information for anti-MFSD2A antibody
Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.
Product Categories/Family for anti-MFSD2A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,266 Da
NCBI Official Full Name
sodium-dependent lysophosphatidylcholine symporter 1-A
NCBI Official Synonym Full Names
major facilitator superfamily domain containing 2aa
NCBI Official Symbol
mfsd2aa
NCBI Official Synonym Symbols
NLS1-A; mfsd2a; zgc:101615
NCBI Protein Information
sodium-dependent lysophosphatidylcholine symporter 1-A
UniProt Protein Name
Sodium-dependent lysophosphatidylcholine symporter 1-A
Protein Family
UniProt Gene Name
mfsd2aa
UniProt Synonym Gene Names
mfsd2a; nls1a; NLS1-A; Sodium-dependent LPC symporter 1-A
UniProt Entry Name
NLS1A_DANRE
Uniprot Description
Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport ().
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Product Notes
The MFSD2A mfsd2aa (Catalog #AAA9405985) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MFSD2A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MFSD2A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the MFSD2A mfsd2aa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MFSD2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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