Rabbit anti-Human, Rat METTL7A Polyclonal Antibody | anti-METTL7A antibody

METTL7A Polyclonal Antibody

Cat. Num. AAA3009077

• Gene Names: METTL7A; AAMB; AAM-B
• Reactivity: Human, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: METTL7A; Polyclonal Antibody; METTL7A Polyclonal Antibody; Protein AAM-B; Methyltransferase-like protein 7A; anti-METTL7A antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: METTL7A polyclonal antibody detects endogenous levels of METTL7A protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 244

• Applicable Applications for anti-METTL7A antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Recombinant protein of human METTL7A.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extract of various cells, using METTL7A antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat liver using METTL7A antibody at dilution of 1:200 (40x lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostate using METTL7A antibody at dilution of 1:200 (40x lens).)

Related Product Information for anti-METTL7A antibody

METTL7A (methyltransferase like 7A), also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1, 100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.

NCBI and Uniprot Product Information

• NCBI GI #: 89145417
• NCBI GeneID: 25840
• NCBI Accession #: NP_054752
• NCBI GenBank Nucleotide #: NP_054752.3
• UniProt Accession #: Q9H8H3
• Molecular Weight: ~ 28kDa
• NCBI Official Full Name: methyltransferase-like protein 7A
• NCBI Official Synonym Full Names: methyltransferase like 7A
• NCBI Official Symbol: METTL7A
• NCBI Official Synonym Symbols: AAMB; AAM-B
• NCBI Protein Information: methyltransferase-like protein 7A
• UniProt Protein Name: Methyltransferase-like protein 7A
• Protein Family: Methyltransferase-like protein
• UniProt Gene Name: METTL7A
• UniProt Entry Name: MET7A_HUMAN

Uniprot Description

METTL7A: Probable methyltransferase. Belongs to the methyltransferase superfamily.

Protein type: Methyltransferase, protein arginine, predicted; Secreted; Methyltransferase; Secreted, signal peptide; EC 2.1.1.-

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: membrane; endoplasmic reticulum; cytoplasm; lipid particle

Molecular Function: S-adenosylmethionine-dependent methyltransferase activity

Biological Process: methylation