Rabbit anti-Human, Mouse MettL7A Polyclonal Antibody | anti-METTL7A antibody

MettL7A Antibody

Cat. Num. AAA150835

• Gene Names: METTL7A; AAM-B
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunocytochemistry, Immunofluorescence
• Purity: MettL7A Antibody is affinity chromatography purified via peptide column.
• Synonyms: MettL7A; Polyclonal Antibody; MettL7A Antibody; AAM-B; Methyltransferase-like protein 7A; Protein AAM-B; methyltransferase like 7A; anti-METTL7A antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least two isoforms of MettL7A are known to exist. This antibody is predicted to not cross-react with MettL7B.
• Purity/Purification: MettL7A Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 244

• Applicable Applications for anti-METTL7A antibody: ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
• Application Notes: MettL7A antibody can be used for detection of MettL7A by Western blot at 2 mug/mL. Antibody can also be used for immunocytochemistry starting at 2 mug/mL. For immunofluorescence start at 2 mug/mL.
• Conjugate: Unconjugated
• Immunogen: MettL7A antibody was raised against a 13 amino acid synthetic peptide near the center of human MettL7A.
• Buffer: MettL7A Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: MettL7A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of MettL7A in MCF cell lysate with MettL7A antibody at 2 μg/mL.)

Immunocytochemistry (IHC)

(Immunocytochemistry of MettL7a in MCF7 cells with MettL7a antibody at 2 μg/mL.)

Related Product Information for anti-METTL7A antibody

MettL7A Antibody: MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

NCBI and Uniprot Product Information

• NCBI GI #: 89145417
• NCBI GeneID: 25840
• NCBI Accession #: NP_054752
• NCBI GenBank Nucleotide #: NM_014033.3
• UniProt Accession #: Q9H8H3; Q9H7R3; Q9UHZ7; Q9Y422
• Molecular Weight: 28,319 Da
• NCBI Official Full Name: methyltransferase-like protein 7A
• NCBI Official Synonym Full Names: methyltransferase like 7A
• NCBI Official Symbol: METTL7A
• NCBI Official Synonym Symbols: AAM-B
• NCBI Protein Information: methyltransferase-like protein 7A; protein AAM-B
• UniProt Protein Name: Methyltransferase-like protein 7A
• Protein Family: Methyltransferase-like protein
• UniProt Gene Name: METTL7A
• UniProt Entry Name: MET7A_HUMAN

Uniprot Description

METTL7A: Probable methyltransferase. Belongs to the methyltransferase superfamily.

Protein type: Methyltransferase, protein arginine, predicted; Secreted; Methyltransferase; Secreted, signal peptide; EC 2.1.1.-

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: membrane; endoplasmic reticulum; cytoplasm; lipid particle

Molecular Function: S-adenosylmethionine-dependent methyltransferase activity

Biological Process: methylation