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Immunohistochemistry (IHC)

Rabbit anti-Mouse, Human MCT4 Polyclonal Antibody | anti-MCT4 antibody

Anti-MCT4 Antibody

Gene Names
SLC16A4; MCT4; MCT5
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
MCT4; Polyclonal Antibody; Anti-MCT4 Antibody; MCT5; Monocarboxylate transporter 5; MCT 5; Monocarboxylate transporter 4; MCT 4; Solute carrier family 16 member 4; anti-MCT4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Affinity purified rabbit polyclonal antibody to detect MCT4 expression in human and mouse samples
Purity/Purification
Affinity purification
Form/Format
Colorless liquid. In 0.42% Potassium phosphate; 0.87% NaCl; pH7.3; 30% glycerol; and 0.01% sodium azide
Applicable Applications for anti-MCT4 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
WB: 1:1000-1:2000
WB data verified using whole cell lysates of mouse skeletal muscle
IHC 1:50-1:200
Immunogen
Recombinant full length protein of human MCT4
Preparation and Storage
Store at -20 degree C
The antibody solution should be gently mixed before use.
Shelf life: ~12 months

Immunohistochemistry (IHC)

Immunohistochemistry (IHC)

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-MCT4 antibody
Monocarboxylate transporter 4 (MCT4), also known as solute carrier family 16 member 3 (SLC16A3) is a proton-coupled lactate transporter protein that facilitates the transport of monocarboxylates such as lactate, pyruvate and ketones across the plasma membrane. MCT4 is expressed in glycolytic tissues such as fast-twitch muscles, neural layer of the retina, chondrocytes and activated macrophages. MCT4 is widely investigated in cancer cells, however the expression in tumor cells depends on tumor type.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
439
NCBI Official Full Name
Monocarboxylate transporter 5
NCBI Official Synonym Full Names
solute carrier family 16, member 4
NCBI Official Symbol
SLC16A4
NCBI Official Synonym Symbols
MCT4; MCT5
NCBI Protein Information
monocarboxylate transporter 5; MCT 4; MCT 5; monocarboxylate transporter 4; solute carrier family 16 (monocarboxylic acid transporters), member 4; solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
UniProt Protein Name
Monocarboxylate transporter 5
UniProt Gene Name
SLC16A4
UniProt Synonym Gene Names
MCT4; MCT5; MCT 5; MCT 4
UniProt Entry Name
MOT5_HUMAN

Uniprot Description

SLC16A4: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: membrane; integral to plasma membrane; integral to membrane

Molecular Function: monocarboxylic acid transmembrane transporter activity; symporter activity

Biological Process: monocarboxylic acid transport

Research Articles on MCT4

Similar Products

Product Notes

The MCT4 slc16a4 (Catalog #AAA847851) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MCT4 Antibody reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's MCT4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). WB: 1:1000-1:2000 WB data verified using whole cell lysates of mouse skeletal muscle IHC 1:50-1:200. Researchers should empirically determine the suitability of the MCT4 slc16a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCT4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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