Western Blot (WB)
(Mouse Mcm2 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Mcm2 antibody detected the Mcm2 protein (arrow).)
Rabbit anti-Mouse Mcm2 Polyclonal Antibody | anti-Mcm2 antibody
Mouse Mcm2 Antibody (C-term)
Gene Names
Mcm2; BM28; CDCL1; Mcmd2; AA959861; AW476101; mKIAA0030
Reactivity
Mouse
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Mcm2; Polyclonal Antibody; Mouse Mcm2 Antibody (C-term); DNA replication licensing factor MCM2; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28; Bm28; Cdcl1; Kiaa0030; Mcmd2; anti-Mcm2 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Mcm2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 713-742 amino acids from the C-terminal region of mouse Mcm2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.45 (varies by lot)
Sequence Positions
713-742
Sequence Length
904
Applicable Applications for anti-Mcm2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
MOUSE
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Mouse Mcm2 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Mcm2 antibody detected the Mcm2 protein (arrow).)
Western Blot (WB)
(Mouse Mcm2 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Mcm2 antibody detected the Mcm2 protein (arrow).)
Related Product Information for anti-Mcm2 antibody
Mcm2 acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for the entry in S phase and for cell division.
References
Kunnev, D., et al. Oncogene 29(25):3630-3638(2010)
Chuang, C.H., et al. PLoS Genet. 6 (9) (2010) :
Lee, E.Y., et al. Dev. Biol. 332(1):104-115(2009)
Hasegawa, M., et al. Leuk. Res. 33(8):1100-1107(2009)
Breunig, J.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(35):13127-13132(2008)
Chuang, C.H., et al. PLoS Genet. 6 (9) (2010) :
Lee, E.Y., et al. Dev. Biol. 332(1):104-115(2009)
Hasegawa, M., et al. Leuk. Res. 33(8):1100-1107(2009)
Breunig, J.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(35):13127-13132(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
102078
NCBI Official Full Name
DNA replication licensing factor MCM2
NCBI Official Synonym Full Names
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
NCBI Official Symbol
Mcm2
NCBI Official Synonym Symbols
BM28; CDCL1; Mcmd2; AA959861; AW476101; mKIAA0030
NCBI Protein Information
DNA replication licensing factor MCM2
UniProt Protein Name
DNA replication licensing factor MCM2
Protein Family
UniProt Gene Name
Mcm2
UniProt Synonym Gene Names
Bm28; Cdcl1; Kiaa0030; Mcmd2
UniProt Entry Name
MCM2_MOUSE
Uniprot Description
MCM2: a mini-chromosome maintenance protein, essential for the initiation of eukaryotic genome replication. Allows DNA to undergo a single round of replication per cell cycle. Required for the entry in S phase and for cell division.
Protein type: DNA-binding; EC 3.6.4.12
Cellular Component: microtubule cytoskeleton; nucleoplasm; MCM complex; cytoplasm; chromatin; nuclear origin of replication recognition complex; nucleus
Molecular Function: DNA helicase activity; DNA binding; histone binding; hydrolase activity; metal ion binding; nucleotide binding; DNA replication origin binding; helicase activity; ATP binding
Biological Process: DNA unwinding during replication; nucleosome assembly; DNA replication initiation; cell cycle; DNA replication
Research Articles on Mcm2
Similar Products
Product Notes
The Mcm2 mcm2 (Catalog #AAA9214447) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 713-742. The Mouse Mcm2 Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Mcm2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Mcm2 mcm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mcm2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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