Immunohistochemistry (IHC)
(Immunohistochemistry analysis using Rabbit Anti-MCL 1 Polyclonal Antibody . Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-MCL 1 Polyclonal Antibody at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.)
Rabbit anti-Mouse; Rat MCL 1 Polyclonal Antibody | anti-MCL 1 antibody
MCL 1 Antibody: HRP
Immunohistochemistry (IHC)
(Immunohistochemistry analysis using Rabbit Anti-MCL 1 Polyclonal Antibody . Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-MCL 1 Polyclonal Antibody at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis using Rabbit Anti-MCL 1 Polyclonal Antibody . Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-MCL 1 Polyclonal Antibody at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.)
Western Blot (WB)
(Western blot analysis of Rat, Mouse Liver showing detection of 37.3 kDa MCL1 protein using Rabbit Anti-MCL1 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Liver. Lane 3: Mouse Liver . Load: 15 ug. Block: 5% Skim Milk powder in TBST. Primary Antibody: Rabbit Anti-MCL1 Polyclonal Antibody at 1:1000 for 2 hours at RT with shaking. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:5000 for 1 hour at RT. Color Development: ECL solution for 5 min at RT. Predicted/Observed Size: 37.3 kDa . Other Band(s): 28.6 kDa .)
Western Blot (WB)
(Western blot analysis of Rat, Mouse Liver showing detection of 37.3 kDa MCL1 protein using Rabbit Anti-MCL1 Polyclonal Antibody . Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat Liver. Lane 3: Mouse Liver . Load: 15 ug. Block: 5% Skim Milk powder in TBST. Primary Antibody: Rabbit Anti-MCL1 Polyclonal Antibody at 1:1000 for 2 hours at RT with shaking. Secondary Antibody: Goat Anti-Rabbit IgG: HRP at 1:5000 for 1 hour at RT. Color Development: ECL solution for 5 min at RT. Predicted/Observed Size: 37.3 kDa . Other Band(s): 28.6 kDa .)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
Uniprot Description
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Research Articles on MCL 1
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Product Notes
The MCL 1 mcl1 (Catalog #AAA8001682) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MCL 1 Antibody: HRP reacts with Mouse; Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MCL 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the MCL 1 mcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCL 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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