Western Blot (WB)
(Mouse Map2k3 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).)
Rabbit anti-Human, mouse Map2k3 Polyclonal Antibody | anti-Map2k3 antibody
Mouse Map2k3 Antibody (Center)
Western Blot (WB)
(Mouse Map2k3 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).)
Western Blot (WB)
(Mouse Map2k3 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).)
Western Blot (WB)
(Western blot analysis of Map2k3 (arrow) using rabbit polyclonal Mouse Map2k3 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Map2k3 gene.)
Western Blot (WB)
(Western blot analysis of Map2k3 (arrow) using rabbit polyclonal Mouse Map2k3 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Map2k3 gene.)
Western Blot (WB)
(Mouse Map2k3 Antibody (Center) western blot analysis in C6 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).)
Western Blot (WB)
(Mouse Map2k3 Antibody (Center) western blot analysis in C6 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).)
Western Blot (WB)
(Mouse Map2k3 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).)
Western Blot (WB)
(Mouse Map2k3 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Map2k3 antibody detected the Map2k3 protein (arrow).)
Remy, G., et al. Cell. Signal. 22(4):660-667(2010)
Behren, A., et al. Oncogene 29(10):1519-1530(2010)
Nagelin, M.H., et al. J. Biol. Chem. 284(45):31303-31314(2009)
Yoshizawa, T., et al. J. Immunol. 183(2):1360-1367(2009)
NCBI and Uniprot Product Information
Uniprot Description
MKK3: a dual-specificity protein kinase of the STE7 family. Activates p38 MAP kinase by phosphorylating a Thr and a Tyr residue in the activation loop. Is activated by cytokines and environmental stress in vivo. A deletion and two point mutants found in colon cancer cell lines. Three splice-variant isoforms have been described.
Protein type: Kinase, protein; Protein kinase, dual-specificity (non-receptor); Protein kinase, STE; EC 2.7.12.2; STE group; STE7 family
Cellular Component: membrane; cytoplasm; intracellular; cytosol
Molecular Function: MAP kinase kinase activity; transferase activity; protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; protein kinase binding; ATP binding; protein kinase activity; receptor signaling protein serine/threonine kinase activity
Biological Process: activation of MAPK activity; positive regulation of transcription, DNA-dependent; positive regulation of protein kinase activity; MAPKKK cascade; inflammatory response; phosphorylation; protein amino acid phosphorylation; regulation of cytokine biosynthetic process; cardiac muscle contraction
Research Articles on Map2k3
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Product Notes
The Map2k3 map2k3 (Catalog #AAA9207812) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 132-160. The Mouse Map2k3 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Map2k3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Map2k3 map2k3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Map2k3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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