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Rabbit Mac-2BP Polyclonal Antibody | anti-Mac-2BP antibody

Mac-2BP Rabbit pAb

Gene Names
LGALS3BP; 90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B
Applications
Western Blot, ELISA
Purity
Affinity Purified
Synonyms
Mac-2BP; Polyclonal Antibody; Mac-2BP Rabbit pAb; Galectin-3-binding protein; Basement membrane autoantigen p105; Lectin galactoside-binding soluble 3-binding protein; Mac-2-binding protein; MAC2BP; Mac-2 BP; Tumor-associated antigen 90K; LGALS3BP; M2BP; anti-Mac-2BP antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Sequence Length
585
Applicable Applications for anti-Mac-2BP antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-2000
ELISA 1:10000-20000
Immunogen
Synthetic peptide from human protein at AA range: 100-160
Cellular Localization
Extracellular Matrix, Secreted
Preparation and Storage
Store at -20 degree C for 1 year.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
galectin-3-binding protein
NCBI Official Synonym Full Names
galectin 3 binding protein
NCBI Official Symbol
LGALS3BP
NCBI Official Synonym Symbols
90K; M2BP; gp90; CyCAP; BTBD17B; MAC-2-BP; TANGO10B
NCBI Protein Information
galectin-3-binding protein
UniProt Protein Name
Galectin-3-binding protein
UniProt Gene Name
LGALS3BP
UniProt Synonym Gene Names
M2BP; MAC2BP; Mac-2 BP
UniProt Entry Name
LG3BP_HUMAN

NCBI Description

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

Uniprot Description

LGALS3BP: Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: extracellular matrix; extracellular region; extracellular space; membrane; proteinaceous extracellular matrix

Molecular Function: scavenger receptor activity

Biological Process: cell adhesion; cellular defense response; platelet degranulation; receptor-mediated endocytosis; signal transduction

Research Articles on Mac-2BP

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Product Notes

The Mac-2BP lgals3bp (Catalog #AAA8541056) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Mac-2BP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-2000 ELISA 1:10000-20000. Researchers should empirically determine the suitability of the Mac-2BP lgals3bp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mac-2BP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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