Western Blot (WB)
(Mouse Gpr68 Antibody (Center) western blot analysis in mouse liver and heart tissue lysates (35ug/lane).This demonstrates the Mouse Gpr68 antibody detected the Mouse Gpr68 protein (arrow).)
Rabbit M Gpr68 Polyclonal Antibody | anti-Gpr68 antibody
M Gpr68 Antibody (Center)
Gene Names
Gpr68; Ogr1; BB131428
Reactivity
Mouse (Predicted Reactivity: Bovine, Human)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
M Gpr68; Polyclonal Antibody; M Gpr68 Antibody (Center); Ovarian cancer G-protein coupled receptor 1; G-protein coupled receptor 68; Sphingosylphosphorylcholine receptor; Gpr68; Ogr1; anti-Gpr68 antibody
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Bovine, Human)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Gpr68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-225 amino acids from the Central region of mouse Gpr68.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
200-225
Sequence Length
365
Applicable Applications for anti-Gpr68 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Crown Antibody
Yes
Antigen Source
Mouse
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Mouse Gpr68 Antibody (Center) western blot analysis in mouse liver and heart tissue lysates (35ug/lane).This demonstrates the Mouse Gpr68 antibody detected the Mouse Gpr68 protein (arrow).)
Western Blot (WB)
(Mouse Gpr68 Antibody (Center) western blot analysis in mouse liver and heart tissue lysates (35ug/lane).This demonstrates the Mouse Gpr68 antibody detected the Mouse Gpr68 protein (arrow).)
Related Product Information for anti-Gpr68 antibody
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Product Categories/Family for anti-Gpr68 antibody
References
Carninci P., et al. Science 309:1559-1563(2005).
Vassilatis D.K., et al. Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003).
Singh L.S., et al. J. Natl. Cancer Inst. 99:1313-1327(2007).
Frick K.K., et al. J. Bone Miner. Res. 24:305-313(2009).
Li H., et al. PLoS ONE 4:E5705-E5705(2009).
Vassilatis D.K., et al. Proc. Natl. Acad. Sci. U.S.A. 100:4903-4908(2003).
Singh L.S., et al. J. Natl. Cancer Inst. 99:1313-1327(2007).
Frick K.K., et al. J. Bone Miner. Res. 24:305-313(2009).
Li H., et al. PLoS ONE 4:E5705-E5705(2009).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41209
NCBI Official Full Name
ovarian cancer G-protein coupled receptor 1
NCBI Official Synonym Full Names
G protein-coupled receptor 68
NCBI Official Symbol
Gpr68
NCBI Official Synonym Symbols
Ogr1; BB131428
NCBI Protein Information
ovarian cancer G-protein coupled receptor 1
UniProt Protein Name
Ovarian cancer G-protein coupled receptor 1
Protein Family
UniProt Gene Name
Gpr68
UniProt Synonym Gene Names
Ogr1
UniProt Entry Name
OGR1_MOUSE
Uniprot Description
GPR68: Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer. Belongs to the G-protein coupled receptor 1 family.
Protein type: Tumor suppressor; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral
Cellular Component: membrane; plasma membrane; integral to membrane
Molecular Function: G-protein coupled receptor activity; signal transducer activity
Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of insulin secretion; signal transduction; negative regulation of monocyte differentiation
Research Articles on Gpr68
Similar Products
Product Notes
The Gpr68 gpr68 (Catalog #AAA9206766) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 200-225. The M Gpr68 Antibody (Center) reacts with Mouse (Predicted Reactivity: Bovine, Human) and may cross-react with other species as described in the data sheet. AAA Biotech's M Gpr68 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Gpr68 gpr68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "M Gpr68, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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