Western Blot (WB)
(Anti- Lumican Picoband antibody, MBS177712, Western blottingAll lanes: Anti Lumican (MBS177712) at 0.5ug/mlLane 1: Mouse Testis Tissue Lysate at 50ugLane 2: Mouse Thymus Tissue Lysate at 50ugLane 3: NIH3T3 Whole Cell Lysate at 40ugPredicted bind size: 38KDObserved bind size: 60KD )
anti-Mouse Lumican Polyclonal Antibody | anti-Lum antibody
Anti-Lumican Antibody
Western Blot Concentration: 0.1-0.5ug/ml
Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml
Western Blot (WB)
(Anti- Lumican Picoband antibody, MBS177712, Western blottingAll lanes: Anti Lumican (MBS177712) at 0.5ug/mlLane 1: Mouse Testis Tissue Lysate at 50ugLane 2: Mouse Thymus Tissue Lysate at 50ugLane 3: NIH3T3 Whole Cell Lysate at 40ugPredicted bind size: 38KDObserved bind size: 60KD )
Western Blot (WB)
(Anti- Lumican Picoband antibody, MBS177712, Western blottingAll lanes: Anti Lumican (MBS177712) at 0.5ug/mlLane 1: Mouse Testis Tissue Lysate at 50ugLane 2: Mouse Thymus Tissue Lysate at 50ugLane 3: NIH3T3 Whole Cell Lysate at 40ugPredicted bind size: 38KDObserved bind size: 60KD )
Immunohistochemistry (IHC)
(Anti- Lumican Picoband antibody, MBS177712, IHC(P)IHC(P): Mouse Brain Tissue )
Immunohistochemistry (IHC)
(Anti- Lumican Picoband antibody, MBS177712, IHC(P)IHC(P): Mouse Brain Tissue )
Background: Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. Lumican is a major keratan sulfate proteoglycan of the cornea but is ubiquitously distributed in most mesenchymal tissues throughout the body. And Lumican is involved in collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. Corneal transparency is possible due to the exact alignment of collagen fibers by lumican (and keratocan) in the intrafibrillar space.
NCBI and Uniprot Product Information
Uniprot Description
LUM: a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]
Protein type: Secreted, signal peptide; Secreted
Cellular Component: extracellular matrix; extracellular region; extracellular space; fibrillar collagen; proteinaceous extracellular matrix
Molecular Function: collagen binding
Biological Process: collagen fibril organization; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transforming growth factor-beta1 production; visual perception
Research Articles on Lum
Similar Products
Product Notes
The Lum lum (Catalog #AAA177712) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Lumican Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Lumican can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). ELISA Concentration: 0.1-0.5ug/ml Western Blot Concentration: 0.1-0.5ug/ml Immunohistochemistry (IHC) Paraffin Concentration: 0.5-1ug/ml. Researchers should empirically determine the suitability of the Lum lum for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lumican, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
