Rabbit CIDEB Polyclonal Antibody | anti-CIDEB antibody

Rabbit Polyclonal to Human CIDEB

Cat. Num. AAA240447

• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: CIDEB; Polyclonal Antibody; Rabbit Polyclonal to Human CIDEB; Anti-CIDEB Antibody (C-Terminus) IHC-plus; CIDE B; Cell death activator CIDE-B; Human CIDEB; anti-CIDEB antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Peptide corresponding to 15 amino acids near the carboxy terminus of human CIDE-B
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide.
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 219

• Applicable Applications for anti-CIDEB antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Application Notes: IHC-P (5 ug/ml), WB; Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
• Target Species: Human
• Immunogen Description: Synthetic peptide from human CIDEB.
• Immunogen Type: Synthetic peptide
• Immunogen: CIDEB antibody was raised against synthetic peptide from human CIDEB.
• Antigen Modification: C-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-CIDEB antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of CIDE-B in Human Small Intestine cells with CIDE-B antibody at 20 ug/ml.)

Western Blot (WB)

(Western blot of CIDE-B in mouse small intestine tissue lysate with CIDE-B antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.)

Related Product Information for anti-CIDEB antibody

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD.

Product Categories/Family for anti-CIDEB antibody

Family: Apoptosis

NCBI and Uniprot Product Information

• NCBI GI #: 93102358
• NCBI GeneID: 27141
• NCBI Accession #: NP_055245.2
• NCBI GenBank Nucleotide #: NM_014430.2
• UniProt Accession #: Q9UHD4; Q546V8; Q9NNW9; D3DS73
• Molecular Weight: 24,678 Da
• NCBI Official Full Name: cell death activator CIDE-B
• NCBI Official Synonym Full Names: cell death-inducing DFFA-like effector b
• NCBI Official Symbol: CIDEB
• NCBI Protein Information: cell death activator CIDE-B
• UniProt Protein Name: Cell death activator CIDE-B
• Protein Family: Cell death activator
• UniProt Gene Name: CIDEB
• UniProt Entry Name: CIDEB_HUMAN

Uniprot Description

CIDEB: Activates apoptosis.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: perinuclear region of cytoplasm; lipid particle; cytosol

Molecular Function: identical protein binding; protein binding

Biological Process: regulation of apoptosis; DNA damage response, signal transduction resulting in induction of apoptosis; apoptosis