Rabbit LSAMP Polyclonal Antibody | anti-LSAMP antibody

LSAMP Antibody

Cat. Num. AAA7107959

• Gene Names: LSAMP; LAMP; IGLON3
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunofluorescence
• Purity: >95%, Protein G purified
• Synonyms: LSAMP; Polyclonal Antibody; LSAMP Antibody; Limbic system-associated membrane protein; IgLON family member 3; IGLON3; LAMP; anti-LSAMP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 361

• Applicable Applications for anti-LSAMP antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:5000; IF: 1:50-1:200
• Immunogen: Recombinant Human Limbic system-associated membrane protein (168-287AA)
• Conjugation: Non-conjugated
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: Rat brain tissue, Rat liver tissue, Mouse brain tissue, Mouse liver tissueAll lanes: LSAMP antibody at 4.2ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 38 KDaObserved band size: 38 KDa)

Immunofluorescence (IF)

(Immunofluorescence staining of A549 cells with MBS7107959 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 degree C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).)

Related Product Information for anti-LSAMP antibody

Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection (By similarity).

Product Categories/Family for anti-LSAMP antibody

Neuroscience

NCBI and Uniprot Product Information

• NCBI GI #: 974576775
• NCBI GeneID: 4045
• NCBI Accession #: NP_001305844.1
• NCBI GenBank Nucleotide #: NM_001318915.1
• UniProt Accession #: Q13449; Q8IV49
• Molecular Weight: 37,393 Da
• NCBI Official Full Name: limbic system-associated membrane protein isoform 2
• NCBI Official Synonym Full Names: limbic system-associated membrane protein
• NCBI Official Symbol: LSAMP
• NCBI Official Synonym Symbols: LAMP; IGLON3
• NCBI Protein Information: limbic system-associated membrane protein
• UniProt Protein Name: Limbic system-associated membrane protein
• UniProt Gene Name: LSAMP
• UniProt Synonym Gene Names: IGLON3; LAMP; LSAMP

NCBI Description

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Uniprot Description

Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection ().