LSAMP recombinant protein

LSAMP Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8121095

• Gene Names: LSAMP; LAMP; IGLON3
• Purity: >97% as determined by SDS-PAGE
• Synonyms: LSAMP; LSAMP Protein; Human; Recombinant (His Tag); Human LSAMP Protein (His Tag); FLJ34254 Protein; FLJ35396 Protein; FLJ37216 Protein; FLJ54658 Protein; IGLON3 Protein; LAMP Protein; limbic system-associated membrane protein; LSAMP recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >97% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Asn315

• Species: Human
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Val 29
• Tag: C-His
• Protein Construction: A DNA sequence encoding the human LSAMP (Q13449)(Met 1-Asn 315), without the pro peptide, was expressed, with a polyhistidine tag at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for LSAMP recombinant protein

Background: The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system structures. The 64-68-kDa glycoprotein limbic system-associated membrane protein (LsAMP) is expressed on the surface of somata and proximal dendrites of neurons. These areas perform cognitive and autonomic functions, also learning, and memory. The functional analysis indicates that LsAMP acts as a selective adhesion molecule, serving as a guidance cue for specific patterns of connectivity, which underlies the normal development of the limbic system. In animal studies there has been found that rats with an increased level of anxiety had 1.6-fold higher expression of the LsAMP gene in the periaqueductal gray compared to rats with a low level of anxiety, indicating a possible role of LsAMP in the regulation of anxiety.

References

Zacco A. et al., 1990, The Journal of Neuroscience. 10(1): 73-90. Pimenta AF. et al., 1996, Gene. 170(2) :189-95.

NCBI and Uniprot Product Information

• NCBI GI #: 45594240
• NCBI GeneID: 4045
• NCBI Accession #: NP_002329.2
• NCBI GenBank Nucleotide #: NM_002338.3
• UniProt Accession #: Q13449; Q8IV49
• Molecular Weight: 37,393 Da
• NCBI Official Full Name: limbic system-associated membrane protein preproprotein
• NCBI Official Synonym Full Names: limbic system-associated membrane protein
• NCBI Official Symbol: LSAMP
• NCBI Official Synonym Symbols: LAMP; IGLON3
• NCBI Protein Information: limbic system-associated membrane protein; IgLON family member 3
• UniProt Protein Name: Limbic system-associated membrane protein
• UniProt Gene Name: LSAMP
• UniProt Synonym Gene Names: IGLON3; LAMP; LSAMP
• UniProt Entry Name: LSAMP_HUMAN