Rabbit anti-Human LRRC6 Polyclonal Antibody | anti-LRRC6 antibody

LRRC6, ID (LRRC6, LRTP, TSLRP, Protein TILB homolog, Leucine-rich repeat-containing protein 6, Leucine-rich testis-specific protein, Testis-specific leucine-rich repeat protein)

Cat. Num. AAA6007720

• Gene Names: LRRC6; LRTP; TSLRP; CILD19
• Reactivity: Human
• Applications: ELISA, Western Blot, Flow Cytometry, Functional Assay
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: LRRC6; Polyclonal Antibody; ID (LRRC6; LRTP; TSLRP; Protein TILB homolog; Leucine-rich repeat-containing protein 6; Leucine-rich testis-specific protein; Testis-specific leucine-rich repeat protein); Anti -LRRC6; anti-LRRC6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-LRRC6 antibody: ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
• Application Notes: Suitable for use in Western Blot, Flow Cytometry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Flow Cytometry: 1:10-50
• Immunogen: LRRC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the Central region of human LRRC6.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(LRRC6 Antibody (Center) western blot analysis in NCI-H460,A549 cell line lysates (35ug/lane).This demonstrates the LRRC6 antibody detected the LRRC6 protein (arrow).)

Flow Cytometry (FC/FACS)

(LRRC6 Antibody (Center) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-LRRC6 antibody

LRRC6 may be involved in spermatocytogenesis or prophase of meiosis (By similarity).

Product Categories/Family for anti-LRRC6 antibody

Antibodies; Abs to Leucine-rich Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 71051963
• NCBI GeneID: 23639
• UniProt Accession #: Q86X45; Q13648; Q4G183
• Molecular Weight: 54,255 Da
• NCBI Official Full Name: LRRC6 protein
• NCBI Official Synonym Full Names: leucine rich repeat containing 6
• NCBI Official Symbol: LRRC6
• NCBI Official Synonym Symbols: LRTP; TSLRP; CILD19
• NCBI Protein Information: protein tilB homolog; protein TILB homolog; testis-specific leucine-rich repeat protein
• UniProt Protein Name: Protein tilB homolog
• Protein Family: Protein
• UniProt Gene Name: LRRC6
• UniProt Synonym Gene Names: LRTP; TSLRP
• UniProt Entry Name: TILB_HUMAN

NCBI Description

The protein encoded by this gene contains several leucine-rich repeat domains and appears to be involved in the motility of cilia. Defects in this gene are a cause of primary ciliary dyskinesia-19 (CILD19). Two transcript variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Dec 2012]

Uniprot Description

LRRC6: Plays a role in motility of cilia. Belongs to the tilb protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 8q24.22

Cellular Component: cytoplasm; cilium

Molecular Function: protein binding

Biological Process: sperm motility; male gonad development

Disease: Ciliary Dyskinesia, Primary, 19